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Page 1
LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL.
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS. Parvin S, et al. Cancer Cell. 2019 Sep 16;36(3):237-249.e6. doi: 10.1016/j.ccell.2019.07.007. Epub 2019 Aug 22. Cancer Cell. 2019. PMID: 31447348 Free PMC article.
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma.
Cubedo E, Gentles AJ, Huang C, Natkunam Y, Bhatt S, Lu X, Jiang X, Romero-Camarero I, Freud A, Zhao S, Bacchi CE, Martínez-Climent JA, Sánchez-García I, Melnick A, Lossos IS. Cubedo E, et al. Blood. 2012 Jun 7;119(23):5478-91. doi: 10.1182/blood-2012-01-403154. Epub 2012 Apr 19. Blood. 2012. PMID: 22517897 Free PMC article.
Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice.
Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, Garcia-Criado FJ, García-Cenador MB, Tousseyn T, Agirre X, Prosper F, Garcia-Bragado F, McPhail ED, Lossos IS, Du MQ, Flores T, Hernandez-Rivas JM, Gonzalez M, Salar A, Bellosillo B, Conde E, Siebert R, Sagaert X, Cobaleda C, Sanchez-Garcia I, Martinez-Climent JA. Vicente-Dueñas C, et al. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10534-9. doi: 10.1073/pnas.1204127109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689981 Free PMC article.
A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.
Vicente-Dueñas C, Romero-Camarero I, González-Herrero I, Alonso-Escudero E, Abollo-Jiménez F, Jiang X, Gutierrez NC, Orfao A, Marín N, Villar LM, Criado MC, Pintado B, Flores T, Alonso-López D, De Las Rivas J, Jiménez R, Criado FJ, Cenador MB, Lossos IS, Cobaleda C, Sánchez-García I. Vicente-Dueñas C, et al. EMBO J. 2012 Sep 12;31(18):3704-17. doi: 10.1038/emboj.2012.227. Epub 2012 Aug 17. EMBO J. 2012. PMID: 22903061 Free PMC article.
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation.
Romero-Camarero I, Jiang X, Natkunam Y, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Zhao S, Segura V, Fontan L, Martínez-Climent JA, García-Criado FJ, Theis JD, Dogan A, Campos-Sánchez E, Green MR, Alizadeh AA, Cobaleda C, Sánchez-García I, Lossos IS. Romero-Camarero I, et al. Nat Commun. 2013;4:1338. doi: 10.1038/ncomms2334. Nat Commun. 2013. PMID: 23299888 Free PMC article.
Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.
Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I. Green MR, et al. Nat Commun. 2014 Jun 2;5:3904. doi: 10.1038/ncomms4904. Nat Commun. 2014. PMID: 24887457 Free PMC article.
Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation.
Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ, Irish J, Stehr H, Vicente-Dueñas C, Romero-Camarero I, Sanchez-Garcia I, Plevritis SK, Arber DA, Batzoglou S, Levy R, Alizadeh AA. Green MR, et al. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1116-25. doi: 10.1073/pnas.1501199112. Epub 2015 Feb 23. Proc Natl Acad Sci U S A. 2015. PMID: 25713363 Free PMC article.
Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.
García-Ramírez I, Bhatia S, Rodríguez-Hernández G, González-Herrero I, Walter C, González de Tena-Dávila S, Parvin S, Haas O, Woessmann W, Stanulla M, Schrappe M, Dugas M, Natkunam Y, Orfao A, Domínguez V, Pintado B, Blanco O, Alonso-López D, De Las Rivas J, Martín-Lorenzo A, Jiménez R, García Criado FJ, García Cenador MB, Lossos IS, Vicente-Dueñas C, Borkhardt A, Hauer J, Sánchez-García I. García-Ramírez I, et al. EMBO J. 2018 Jul 13;37(14):e98783. doi: 10.15252/embj.201798783. Epub 2018 Jun 7. EMBO J. 2018. PMID: 29880602 Free PMC article.
Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling.
Jiang X, Lu X, Zhang Y, Lacaria L, Schuchardt BJ, Mikles DC, Magistri M, García-Ramírez I, Sanchez-Garcia I, Farooq A, Verdun RE, Abdulreda MH, Moy VT, Lossos IS. Jiang X, et al. Blood Adv. 2019 Aug 13;3(15):2286-2297. doi: 10.1182/bloodadvances.2018016162. Blood Adv. 2019. PMID: 31362927 Free PMC article.
157 results