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Immunisation of cattle against Babesia bovis combining a multi-epitope modified vaccinia Ankara virus and a recombinant protein induce strong Th1 cell responses but fails to trigger neutralising antibodies required for protection.
Jaramillo Ortiz JM, Paoletta MS, Gravisaco MJ, López Arias LS, Montenegro VN, de la Fournière SAM, Valenzano MN, Guillemi EC, Valentini B, Echaide I, Farber MD, Wilkowsky SE. Jaramillo Ortiz JM, et al. Among authors: valenzano mn. Ticks Tick Borne Dis. 2019 Oct;10(6):101270. doi: 10.1016/j.ttbdis.2019.101270. Epub 2019 Aug 16. Ticks Tick Borne Dis. 2019. PMID: 31445874
A prime-boost combination of a three-protein cocktail and multiepitopic MVA as a vaccine against Babesia bigemina elicits neutralizing antibodies and a Th1 cellular immune response in mice.
Montenegro VN, Jaramillo-Ortiz JM, Paoletta MS, Gravisaco MJ, Del Médico Zajac MP, Garanzini DP, Valenzano MN, Calamante G, Wilkowsky SE. Montenegro VN, et al. Among authors: valenzano mn. Ticks Tick Borne Dis. 2022 Sep;13(5):101991. doi: 10.1016/j.ttbdis.2022.101991. Epub 2022 Jun 23. Ticks Tick Borne Dis. 2022. PMID: 35792436