Machado-Neto JA - Search Results

1

Stathmin 1 is highly expressed and associated with survival outcome in malignant adrenocortical tumours.

Dos Santos Passaia B, Lima K, Kremer JL, da Conceição BB, de Paula Mariani BM, da Silva JCL, Zerbini MCN, Fragoso MCBV, Machado-Neto JA, Lotfi CFP. Dos Santos Passaia B, et al. Invest New Drugs. 2020 Jun;38(3):899-908. doi: 10.1007/s10637-019-00846-9. Epub 2019 Aug 22. Invest New Drugs. 2020. PMID: 31441020

2

Monoolein-based nanodispersions for cutaneous co-delivery of methylene blue and metformin: Thermal and structural characterization and effects on the cutaneous barrier, skin penetration and cytotoxicity.

Donadon LGF, Salata GC, Gonçalves TP, Matos LC, Evangelista MCP, da Silva NS, Martins TS, Machado-Neto JA, Lopes LB, Garcia MTJ. Donadon LGF, et al. Int J Pharm. 2023 Feb 25;633:122612. doi: 10.1016/j.ijpharm.2023.122612. Epub 2023 Jan 13. Int J Pharm. 2023. PMID: 36642349

3

Differential profile of PIP4K2A expression in hematological malignancies.

Lima K, Ribeiro DM, Campos Pde M, Costa FF, Traina F, Saad ST, Sonati Mde F, Machado-Neto JA. Lima K, et al. Blood Cells Mol Dis. 2015 Oct;55(3):228-35. doi: 10.1016/j.bcmd.2015.06.014. Epub 2015 Jun 30. Blood Cells Mol Dis. 2015. PMID: 26227852

4

PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia.

Lima K, Coelho-Silva JL, Kinker GS, Pereira-Martins DA, Traina F, Fernandes PACM, Markus RP, Lucena-Araujo AR, Machado-Neto JA. Lima K, et al. Cancer Genet. 2019 Apr;233-234:56-66. doi: 10.1016/j.cancergen.2019.04.002. Epub 2019 Apr 11. Cancer Genet. 2019. PMID: 31109595

5

Reversine exhibits antineoplastic activity in JAK2^V617F-positive myeloproliferative neoplasms.

Lima K, Carlos JAEG, Alves-Paiva RM, Vicari HP, Souza Santos FP, Hamerschlak N, Costa-Lotufo LV, Traina F, Machado-Neto JA. Lima K, et al. Sci Rep. 2019 Jul 9;9(1):9895. doi: 10.1038/s41598-019-46163-2. Sci Rep. 2019. PMID: 31289316 Free PMC article.

6

Reversine exerts cytotoxic effects through multiple cell death mechanisms in acute lymphoblastic leukemia.

Carlos JAEG, Lima K, Coelho-Silva JL, de Melo Alves-Paiva R, Moreno NC, Vicari HP, de Souza Santos FP, Hamerschlak N, Costa-Lotufo LV, Traina F, Machado-Neto JA. Carlos JAEG, et al. Cell Oncol (Dordr). 2020 Dec;43(6):1191-1201. doi: 10.1007/s13402-020-00551-3. Epub 2020 Aug 28. Cell Oncol (Dordr). 2020. PMID: 32857324

7

Exploring redox vulnerabilities in JAK2^V617F-positive cellular models.

Lima K, Lopes LR, Machado-Neto JA. Lima K, et al. Hematol Transfus Cell Ther. 2021 Oct-Dec;43(4):430-436. doi: 10.1016/j.htct.2020.08.006. Epub 2020 Sep 13. Hematol Transfus Cell Ther. 2021. PMID: 32962959 Free PMC article.

8

NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia.

Scopim-Ribeiro R, Machado-Neto JA, Eide CA, Coelho-Silva JL, Fenerich BA, Fernandes JC, Scheucher PS, Savage Stevens SL, de Melo Campos P, Olalla Saad ST, de Carvalho Palma L, de Figueiredo-Pontes LL, Simões BP, Rego EM, Tognon CE, Druker BJ, Traina F. Scopim-Ribeiro R, et al. Invest New Drugs. 2021 Jun;39(3):736-746. doi: 10.1007/s10637-020-01028-8. Epub 2021 Jan 6. Invest New Drugs. 2021. PMID: 33403501

9

Synthetic cyclopenta[b]indoles exhibit antineoplastic activity by targeting microtubule dynamics in acute myeloid leukemia cells.

Vicari HP, Lima K, Gomes RDC, Fernandes DC, da Silva JCL, Rodrigues Junior MT, Barroso de Oliveira AS, Dos Santos RN, Andricopulo AD, Coelho F, Costa-Lotufo LV, Machado-Neto JA. Vicari HP, et al. Eur J Pharmacol. 2021 Mar 5;894:173853. doi: 10.1016/j.ejphar.2021.173853. Epub 2021 Jan 8. Eur J Pharmacol. 2021. PMID: 33422507

10

AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis.

Carlos JAEG, Lima K, Costa-Lotufo LV, Leitão A, Machado-Neto JA. Carlos JAEG, et al. Invest New Drugs. 2021 Aug;39(4):1139-1149. doi: 10.1007/s10637-021-01066-w. Epub 2021 Jan 21. Invest New Drugs. 2021. PMID: 33475938

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