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Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Buter J, Cheng TY, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN, Layre E, Ramnarine AK, Mayfield JA, Young DC, Jezek Martinot A, Siddiqi N, Wakabayashi S, Botella H, Calderon R, Murray M, Ehrt S, Snider BB, Reed MB, Oldfield E, Tan S, Rubin EJ, Behr MA, van der Wel NN, Minnaard AJ, Moody DB. Buter J, et al. Among authors: minnaard aj. Nat Chem Biol. 2019 Sep;15(9):889-899. doi: 10.1038/s41589-019-0336-0. Epub 2019 Aug 19. Nat Chem Biol. 2019. PMID: 31427817 Free PMC article.
A comparative lipidomics platform for chemotaxonomic analysis of Mycobacterium tuberculosis.
Layre E, Sweet L, Hong S, Madigan CA, Desjardins D, Young DC, Cheng TY, Annand JW, Kim K, Shamputa IC, McConnell MJ, Debono CA, Behar SM, Minnaard AJ, Murray M, Barry CE 3rd, Matsunaga I, Moody DB. Layre E, et al. Among authors: minnaard aj. Chem Biol. 2011 Dec 23;18(12):1537-49. doi: 10.1016/j.chembiol.2011.10.013. Chem Biol. 2011. PMID: 22195556 Free PMC article.
Saposins utilize two strategies for lipid transfer and CD1 antigen presentation.
León L, Tatituri RV, Grenha R, Sun Y, Barral DC, Minnaard AJ, Bhowruth V, Veerapen N, Besra GS, Kasmar A, Peng W, Moody DB, Grabowski GA, Brenner MB. León L, et al. Among authors: minnaard aj. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4357-64. doi: 10.1073/pnas.1200764109. Epub 2012 Feb 13. Proc Natl Acad Sci U S A. 2012. PMID: 22331868 Free PMC article.
CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.
Ly D, Kasmar AG, Cheng TY, de Jong A, Huang S, Roy S, Bhatt A, van Summeren RP, Altman JD, Jacobs WR Jr, Adams EJ, Minnaard AJ, Porcelli SA, Moody DB. Ly D, et al. Among authors: minnaard aj. J Exp Med. 2013 Apr 8;210(4):729-41. doi: 10.1084/jem.20120624. Epub 2013 Mar 25. J Exp Med. 2013. PMID: 23530121 Free PMC article.
Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c.
Layre E, Lee HJ, Young DC, Martinot AJ, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB. Layre E, et al. Among authors: minnaard aj. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2978-83. doi: 10.1073/pnas.1315883111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516143 Free PMC article.
194 results