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Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Buter J, Cheng TY, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN, Layre E, Ramnarine AK, Mayfield JA, Young DC, Jezek Martinot A, Siddiqi N, Wakabayashi S, Botella H, Calderon R, Murray M, Ehrt S, Snider BB, Reed MB, Oldfield E, Tan S, Rubin EJ, Behr MA, van der Wel NN, Minnaard AJ, Moody DB. Buter J, et al. Among authors: grootemaat ae. Nat Chem Biol. 2019 Sep;15(9):889-899. doi: 10.1038/s41589-019-0336-0. Epub 2019 Aug 19. Nat Chem Biol. 2019. PMID: 31427817 Free PMC article.
Interfering With DNA Decondensation as a Strategy Against Mycobacteria.
Scutigliani EM, Scholl ER, Grootemaat AE, Khanal S, Kochan JA, Krawczyk PM, Reits EA, Garzan A, Ngo HX, Green KD, Garneau-Tsodikova S, Ruijter JM, van Veen HA, van der Wel NN. Scutigliani EM, et al. Among authors: grootemaat ae. Front Microbiol. 2018 Sep 5;9:2034. doi: 10.3389/fmicb.2018.02034. eCollection 2018. Front Microbiol. 2018. PMID: 30233521 Free PMC article.
Extravasation of Microspheres in a Rat Model of Silent Brain Infarcts.
van der Wijk AE, Lachkar N, de Vos J, Grootemaat AE, van der Wel NN, Hordijk PL, Bakker ENTP, vanBavel E. van der Wijk AE, et al. Among authors: grootemaat ae. Stroke. 2019 Jun;50(6):1590-1594. doi: 10.1161/STROKEAHA.119.024975. Epub 2019 Apr 18. Stroke. 2019. PMID: 31136287
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo.
van der Niet S, van Zon M, de Punder K, Grootemaat A, Rutten S, Moorlag SJCFM, Houben D, van der Sar AM, Bitter W, Brosch R, Hernandez Pando R, Pena MT, Peters PJ, Reits EA, Mayer-Barber KD, van der Wel NN. van der Niet S, et al. mSphere. 2021 May 5;6(3):e00153-21. doi: 10.1128/mSphere.00153-21. mSphere. 2021. PMID: 33952660 Free PMC article.
The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages.
Gómez-Mellado VE, Ho-Mok KS, van der Mark VA, van der Wel NN, Grootemaat AE, Verhoeven AJ, Elferink RPJO, Paulusma CC. Gómez-Mellado VE, et al. Among authors: grootemaat ae. Cell Biochem Funct. 2022 Dec;40(8):914-925. doi: 10.1002/cbf.3752. Epub 2022 Sep 28. Cell Biochem Funct. 2022. PMID: 36169099 Free PMC article.
A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.
Bedard M, van der Niet S, Bernard EM, Babunovic G, Cheng TY, Aylan B, Grootemaat AE, Raman S, Botella L, Ishikawa E, O'Sullivan MP, O'Leary S, Mayfield JA, Buter J, Minnaard AJ, Fortune SM, Murphy LO, Ory DS, Keane J, Yamasaki S, Gutierrez MG, van der Wel N, Moody DB. Bedard M, et al. Among authors: grootemaat ae. J Clin Invest. 2023 Mar 15;133(6):e161944. doi: 10.1172/JCI161944. J Clin Invest. 2023. PMID: 36757797 Free PMC article.
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