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Real-time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality.
Biotechnol Prog. 2019 Nov;35(6):e2894. doi: 10.1002/btpr.2894. Epub 2019 Aug 28.
Biotechnol Prog. 2019.
PMID: 31425633
Free PMC article.
Multivariate data analysis of growth medium trends affecting antibody glycosylation.
Powers DN, Trunfio N, Velugula-Yellela SR, Angart P, Faustino A, Agarabi C.
Powers DN, et al. Among authors: velugula yellela sr.
Biotechnol Prog. 2020 Jan;36(1):e2903. doi: 10.1002/btpr.2903. Epub 2019 Oct 18.
Biotechnol Prog. 2020.
PMID: 31487120
Free PMC article.
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Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro-bioreactor system.
Velugula-Yellela SR, Williams A, Trunfio N, Hsu CJ, Chavez B, Yoon S, Agarabi C.
Velugula-Yellela SR, et al.
Biotechnol Prog. 2018 Jan;34(1):262-270. doi: 10.1002/btpr.2575. Epub 2017 Nov 16.
Biotechnol Prog. 2018.
PMID: 29086492
Free PMC article.
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Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells.
Velugula-Yellela SR, Kohnhorst C, Powers DN, Trunfio N, Faustino A, Angart P, Berilla E, Faison T, Agarabi C.
Velugula-Yellela SR, et al.
J Vis Exp. 2018 Sep 28;(139):58231. doi: 10.3791/58231.
J Vis Exp. 2018.
PMID: 30320757
Free PMC article.
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Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System.
Velugula-Yellela SR, Powers DN, Angart P, Faustino A, Faison T, Kohnhorst C, Fratz-Berilla EJ, Agarabi CD.
Velugula-Yellela SR, et al.
J Vis Exp. 2019 May 1;(147). doi: 10.3791/58947.
J Vis Exp. 2019.
PMID: 31107445
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Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures.
Fratz-Berilla EJ, Faison T, Kohnhorst CL, Velugula-Yellela SR, Powers DN, Brorson K, Agarabi C.
Fratz-Berilla EJ, et al. Among authors: velugula yellela sr.
Biotechnol Bioeng. 2019 Dec;116(12):3242-3252. doi: 10.1002/bit.27161. Epub 2019 Sep 11.
Biotechnol Bioeng. 2019.
PMID: 31478189
Free PMC article.
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Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events.
Fratz-Berilla EJ, Angart P, Graham RJ, Powers DN, Mohammad A, Kohnhorst C, Faison T, Velugula-Yellela SR, Trunfio N, Agarabi C.
Fratz-Berilla EJ, et al. Among authors: velugula yellela sr.
Biotechnol Bioeng. 2020 Sep;117(9):2802-2815. doi: 10.1002/bit.27436. Epub 2020 Jun 4.
Biotechnol Bioeng. 2020.
PMID: 32436993
Free PMC article.
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Bioprocess: Robustness with Respect to Mycoplasma Species.
Faison T, Wang J, Johnson S, Brown M, Chiang MJ, Dolan S, Breuning C, Velugula-Yellela SR, Lute S, Fratz-Berilla EJ, Brorson K.
Faison T, et al. Among authors: velugula yellela sr.
PDA J Pharm Sci Technol. 2020 Mar-Apr;74(2):201-212. doi: 10.5731/pdajpst.2018.009613. Epub 2019 Sep 13.
PDA J Pharm Sci Technol. 2020.
PMID: 31519782
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