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Cytometry by time of flight identifies distinct signatures in patients with systemic sclerosis, systemic lupus erythematosus and Sjögrens syndrome.
van der Kroef M, van den Hoogen LL, Mertens JS, Blokland SLM, Haskett S, Devaprasad A, Carvalheiro T, Chouri E, Vazirpanah N, Cossu M, Wichers CGK, Silva-Cardoso SC, Affandi AJ, Bekker CPJ, Lopes AP, Hillen MR, Bonte-Mineur F, Kok MR, Beretta L, Rossato M, Mingueneau M, van Roon JAG, Radstake TRDJ. van der Kroef M, et al. Among authors: mertens js. Eur J Immunol. 2020 Jan;50(1):119-129. doi: 10.1002/eji.201948129. Epub 2019 Sep 11. Eur J Immunol. 2020. PMID: 31424086 Free article.
Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis.
Chouri E, Servaas NH, Bekker CPJ, Affandi AJ, Cossu M, Hillen MR, Angiolilli C, Mertens JS, van den Hoogen LL, Silva-Cardoso S, van der Kroef M, Vazirpanah N, Wichers CGK, Carvalheiro T, Blokland SLM, Giovannone B, Porretti L, Marut W, Vigone B, van Roon JAG, Beretta L, Rossato M, Radstake TRDJ. Chouri E, et al. Among authors: mertens js. J Autoimmun. 2018 May;89:162-170. doi: 10.1016/j.jaut.2017.12.015. Epub 2018 Jan 20. J Autoimmun. 2018. PMID: 29371048 Free article.
Galectin-9 is an easy to measure biomarker for the interferon signature in systemic lupus erythematosus and antiphospholipid syndrome.
van den Hoogen LL, van Roon JAG, Mertens JS, Wienke J, Lopes AP, de Jager W, Rossato M, Pandit A, Wichers CGK, van Wijk F, Fritsch-Stork RDE, Radstake TRDJ. van den Hoogen LL, et al. Among authors: mertens js. Ann Rheum Dis. 2018 Dec;77(12):1810-1814. doi: 10.1136/annrheumdis-2018-213497. Epub 2018 Sep 5. Ann Rheum Dis. 2018. PMID: 30185417
Galectin-9 reflects the interferon signature and correlates with disease activity in systemic autoimmune diseases. Response to: 'Biomarkers: to be or not to be' by Yavuz and Rönnblom.
van den Hoogen LL, van der Heijden EHM, Hillen MR, Mertens JS, Fritsch-Stork RDE, Radstake TRDJ, van Roon JAG. van den Hoogen LL, et al. Among authors: mertens js. Ann Rheum Dis. 2020 Jan;79(1):e9. doi: 10.1136/annrheumdis-2018-214651. Epub 2018 Dec 8. Ann Rheum Dis. 2020. PMID: 30530825 No abstract available.
Induction of Inflammation and Fibrosis by Semaphorin 4A in Systemic Sclerosis.
Carvalheiro T, Affandi AJ, Malvar-Fernández B, Dullemond I, Cossu M, Ottria A, Mertens JS, Giovannone B, Bonte-Mineur F, Kok MR, Marut W, Reedquist KA, Radstake TR, García S. Carvalheiro T, et al. Among authors: mertens js. Arthritis Rheumatol. 2019 Oct;71(10):1711-1722. doi: 10.1002/art.40915. Epub 2019 Aug 27. Arthritis Rheumatol. 2019. PMID: 31012544 Free PMC article.
Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis.
Affandi AJ, Carvalheiro T, Ottria A, Broen JC, Bossini-Castillo L, Tieland RG, Bon LV, Chouri E, Rossato M, Mertens JS, Garcia S, Pandit A, de Kroon LM, Christmann RB, Martin J, van Roon JA, Radstake TR, Marut W. Affandi AJ, et al. Among authors: mertens js. Ann Rheum Dis. 2019 Sep;78(9):1249-1259. doi: 10.1136/annrheumdis-2018-214991. Epub 2019 May 24. Ann Rheum Dis. 2019. PMID: 31126957
cDC2 and plasmacytoid dendritic cells diminish from tissues of patients with non-Hodgkin orbital lymphoma and idiopathic orbital inflammation.
Laban KG, Rijken R, Hiddingh S, Mertens JS, van der Veen RLP, Eenhorst CAE, Pandit A, Radstake TRDJ, de Boer JH, Kalmann R, Kuiper JJW. Laban KG, et al. Among authors: mertens js. Eur J Immunol. 2020 Apr;50(4):548-557. doi: 10.1002/eji.201948370. Epub 2020 Jan 16. Eur J Immunol. 2020. PMID: 31841217 Free PMC article.
Morphea and Eosinophilic Fasciitis: An Update.
Mertens JS, Seyger MMB, Thurlings RM, Radstake TRDJ, de Jong EMGJ. Mertens JS, et al. Am J Clin Dermatol. 2017 Aug;18(4):491-512. doi: 10.1007/s40257-017-0269-x. Am J Clin Dermatol. 2017. PMID: 28303481 Free PMC article. Review.
Biomarker profiles of endothelial activation and dysfunction in rare systemic autoimmune diseases: implications for cardiovascular risk.
Wienke J, Mertens JS, Garcia S, Lim J, Wijngaarde CA, Yeo JG, Meyer A, van den Hoogen LL, Tekstra J, Hoogendijk JE, Otten HG, Fritsch-Stork RDE, de Jager W, Seyger MMB, Thurlings RM, de Jong EMGJ, van der Kooi AJ, van der Pol WL; Dutch Juvenile Myositis Consortium; Arkachaisri T, Radstake TRDJ, van Royen-Kerkhof A, van Wijk F. Wienke J, et al. Among authors: mertens js. Rheumatology (Oxford). 2021 Feb 1;60(2):785-801. doi: 10.1093/rheumatology/keaa270. Rheumatology (Oxford). 2021. PMID: 32810267
The identification of CCL18 as biomarker of disease activity in localized scleroderma.
Mertens JS, de Jong EMGJ, van den Hoogen LL, Wienke J, Thurlings RM, Seyger MMB, Hoppenreijs EPAH, Wijngaarde CA, van Vlijmen-Willems IMJJ, van den Bogaard E, Giovannone B, van Wijk F, van Royen-Kerkhof A, Marut W, Radstake TRD. Mertens JS, et al. J Autoimmun. 2019 Jul;101:86-93. doi: 10.1016/j.jaut.2019.04.008. Epub 2019 Apr 18. J Autoimmun. 2019. PMID: 31006523
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