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An overview of activity-based probes for glycosidases.
Wu L, Armstrong Z, Schröder SP, de Boer C, Artola M, Aerts JM, Overkleeft HS, Davies GJ. Wu L, et al. Among authors: armstrong z. Curr Opin Chem Biol. 2019 Dec;53:25-36. doi: 10.1016/j.cbpa.2019.05.030. Epub 2019 Aug 13. Curr Opin Chem Biol. 2019. PMID: 31419756 Review.
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
Armstrong Z, Kuo CL, Lahav D, Liu B, Johnson R, Beenakker TJM, de Boer C, Wong CS, van Rijssel ER, Debets MF, Florea BI, Hissink C, Boot RG, Geurink PP, Ovaa H, van der Stelt M, van der Marel GM, Codée JDC, Aerts JMFG, Wu L, Overkleeft HS, Davies GJ. Armstrong Z, et al. J Am Chem Soc. 2020 Jul 29;142(30):13021-13029. doi: 10.1021/jacs.0c03880. Epub 2020 Jul 16. J Am Chem Soc. 2020. PMID: 32605368
Activity-Based Protein Profiling of Retaining α-Amylases in Complex Biological Samples.
Chen Y, Armstrong Z, Artola M, Florea BI, Kuo CL, de Boer C, Rasmussen MS, Abou Hachem M, van der Marel GA, Codée JDC, Aerts JMFG, Davies GJ, Overkleeft HS. Chen Y, et al. Among authors: armstrong z. J Am Chem Soc. 2021 Feb 10;143(5):2423-2432. doi: 10.1021/jacs.0c13059. Epub 2021 Jan 26. J Am Chem Soc. 2021. PMID: 33497208 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33506786
Synthesis of broad-specificity activity-based probes for exo-β-mannosidases.
McGregor NGS, Kuo CL, Beenakker TJM, Wong CS, Offen WA, Armstrong Z, Florea BI, Codée JDC, Overkleeft HS, Aerts JMFG, Davies GJ. McGregor NGS, et al. Among authors: armstrong z. Org Biomol Chem. 2022 Jan 26;20(4):877-886. doi: 10.1039/d1ob02287c. Org Biomol Chem. 2022. PMID: 35015006 Free PMC article.
The structure of Phocaeicola vulgatus sialic acid acetylesterase.
Scott H, Davies GJ, Armstrong Z. Scott H, et al. Among authors: armstrong z. Acta Crystallogr D Struct Biol. 2022 May 1;78(Pt 5):647-657. doi: 10.1107/S2059798322003357. Epub 2022 Apr 26. Acta Crystallogr D Struct Biol. 2022. PMID: 35503212 Free PMC article.
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.
de Boer C, Armstrong Z, Lit VAJ, Barash U, Ruijgrok G, Boyango I, Weitzenberg MM, Schröder SP, Sarris AJC, Meeuwenoord NJ, Bule P, Kayal Y, Ilan N, Codée JDC, Vlodavsky I, Overkleeft HS, Davies GJ, Wu L. de Boer C, et al. Among authors: armstrong z. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203167119. doi: 10.1073/pnas.2203167119. Epub 2022 Jul 26. Proc Natl Acad Sci U S A. 2022. PMID: 35881786 Free PMC article.
β-l-Arabinofurano-cyclitol Aziridines Are Covalent Broad-Spectrum Inhibitors and Activity-Based Probes for Retaining β-l-Arabinofuranosidases.
Borlandelli V, Offen W, Moroz O, Nin-Hill A, McGregor N, Binkhorst L, Ishiwata A, Armstrong Z, Artola M, Rovira C, Davies GJ, Overkleeft HS. Borlandelli V, et al. Among authors: armstrong z. ACS Chem Biol. 2023 Dec 15;18(12):2564-2573. doi: 10.1021/acschembio.3c00558. Epub 2023 Dec 5. ACS Chem Biol. 2023. PMID: 38051515 Free PMC article.
57 results