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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas.
Hsieh MH, Choe JH, Gadhvi J, Kim YJ, Arguez MA, Palmer M, Gerold H, Nowak C, Do H, Mazambani S, Knighton JK, Cha M, Goodwin J, Kang MK, Jeong JY, Lee SY, Faubert B, Xuan Z, Abel ED, Scafoglio C, Shackelford DB, Minna JD, Singh PK, Shulaev V, Bleris L, Hoyt K, Kim J, Inoue M, DeBerardinis RJ, Kim TH, Kim JW. Hsieh MH, et al. Among authors: goodwin j. Cell Rep. 2019 Aug 13;28(7):1860-1878.e9. doi: 10.1016/j.celrep.2019.07.027. Cell Rep. 2019. PMID: 31412252 Free PMC article.
The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.
Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, Yoo H, Chen M, Ahn JM, Minna JD, Helke KL, Singh PK, Shackelford DB, Kim JW. Goodwin J, et al. Nat Commun. 2017 May 26;8:15503. doi: 10.1038/ncomms15503. Nat Commun. 2017. PMID: 28548087 Free PMC article.
A New Perspective on the Heterogeneity of Cancer Glycolysis.
Neugent ML, Goodwin J, Sankaranarayanan I, Yetkin CE, Hsieh MH, Kim JW. Neugent ML, et al. Among authors: goodwin j. Biomol Ther (Seoul). 2018 Jan 1;26(1):10-18. doi: 10.4062/biomolther.2017.210. Biomol Ther (Seoul). 2018. PMID: 29212302 Free PMC article. Review.
NQO1 inhibits proteasome-mediated degradation of HIF-1α.
Oh ET, Kim JW, Kim JM, Kim SJ, Lee JS, Hong SS, Goodwin J, Ruthenborg RJ, Jung MG, Lee HJ, Lee CH, Park ES, Kim C, Park HJ. Oh ET, et al. Among authors: goodwin j. Nat Commun. 2016 Dec 14;7:13593. doi: 10.1038/ncomms13593. Nat Commun. 2016. PMID: 27966538 Free PMC article.
1,757 results