Males A - Search Results

1

Distortion of mannoimidazole supports a B_2,5 boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens.

Males A, Speciale G, Williams SJ, Davies GJ. Males A, et al. Org Biomol Chem. 2019 Aug 28;17(34):7863-7869. doi: 10.1039/c9ob01161g. Org Biomol Chem. 2019. PMID: 31407758

2

Computational Design of Experiment Unveils the Conformational Reaction Coordinate of GH125 α-Mannosidases.

Alonso-Gil S, Males A, Fernandes PZ, Williams SJ, Davies GJ, Rovira C. Alonso-Gil S, et al. Among authors: males a. J Am Chem Soc. 2017 Jan 25;139(3):1085-1088. doi: 10.1021/jacs.6b11247. Epub 2017 Jan 3. J Am Chem Soc. 2017. PMID: 28026180 Free article.

3

Conformational Behaviour of Azasugars Based on Mannuronic Acid.

van Rijssel ER, Janssen APA, Males A, Davies GJ, van der Marel GA, Overkleeft HS, Codée JDC. van Rijssel ER, et al. Among authors: males a. Chembiochem. 2017 Jul 4;18(13):1297-1304. doi: 10.1002/cbic.201700080. Epub 2017 Apr 18. Chembiochem. 2017. PMID: 28256791 Free article.

4

Conformational Analysis of the Mannosidase Inhibitor Kifunensine: A Quantum Mechanical and Structural Approach.

Males A, Raich L, Williams SJ, Rovira C, Davies GJ. Males A, et al. Chembiochem. 2017 Aug 4;18(15):1496-1501. doi: 10.1002/cbic.201700166. Epub 2017 Jun 26. Chembiochem. 2017. PMID: 28493500

5

Structural studies of a surface-entropy reduction mutant of O-GlcNAcase.

Males A, Davies GJ. Males A, et al. Acta Crystallogr D Struct Biol. 2019 Jan 1;75(Pt 1):70-78. doi: 10.1107/S2059798318016595. Epub 2019 Jan 8. Acta Crystallogr D Struct Biol. 2019. PMID: 30644846 Free PMC article.

6

A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites.

Sernee MF, Ralton JE, Nero TL, Sobala LF, Kloehn J, Vieira-Lara MA, Cobbold SA, Stanton L, Pires DEV, Hanssen E, Males A, Ward T, Bastidas LM, van der Peet PL, Parker MW, Ascher DB, Williams SJ, Davies GJ, McConville MJ. Sernee MF, et al. Among authors: males a. Cell Host Microbe. 2019 Sep 11;26(3):385-399.e9. doi: 10.1016/j.chom.2019.08.009. Cell Host Microbe. 2019. PMID: 31513773 Free article.

7

Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)-processing enzymes.

King DT, Males A, Davies GJ, Vocadlo DJ. King DT, et al. Among authors: males a. Curr Opin Chem Biol. 2019 Dec;53:131-144. doi: 10.1016/j.cbpa.2019.09.001. Epub 2019 Oct 22. Curr Opin Chem Biol. 2019. PMID: 31654859 Review.

8

Mannosidase mechanism: at the intersection of conformation and catalysis.

Rovira C, Males A, Davies GJ, Williams SJ. Rovira C, et al. Among authors: males a. Curr Opin Struct Biol. 2020 Jun;62:79-92. doi: 10.1016/j.sbi.2019.11.008. Epub 2019 Dec 28. Curr Opin Struct Biol. 2020. PMID: 31891872 Free article. Review.

9

Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on α-1,6 Mannanases.

Schröder SP, Offen WA, Males A, Jin Y, de Boer C, Enotarpi J, Marino L, van der Marel GA, Florea BI, Codée JDC, Overkleeft HS, Davies GJ. Schröder SP, et al. Among authors: males a. Chemistry. 2021 Jul 2;27(37):9519-9523. doi: 10.1002/chem.202101255. Epub 2021 May 21. Chemistry. 2021. PMID: 33878235 Free PMC article.

10

Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications.

González-Cuesta M, Sidhu P, Ashmus RA, Males A, Proceviat C, Madden Z, Rogalski JC, Busmann JA, Foster LJ, García Fernández JM, Davies GJ, Ortiz Mellet C, Vocadlo DJ. González-Cuesta M, et al. Among authors: males a. J Am Chem Soc. 2022 Jan 19;144(2):832-844. doi: 10.1021/jacs.1c10504. Epub 2022 Jan 5. J Am Chem Soc. 2022. PMID: 34985906

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