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CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan.
Vennin C, Mélénec P, Rouet R, Nobis M, Cazet AS, Murphy KJ, Herrmann D, Reed DA, Lucas MC, Warren SC, Elgundi Z, Pinese M, Kalna G, Roden D, Samuel M, Zaratzian A, Grey ST, Da Silva A, Leung W; Australian Pancreatic Genome Initiative (APGI); Mathivanan S, Wang Y, Braithwaite AW, Christ D, Benda A, Parkin A, Phillips PA, Whitelock JM, Gill AJ, Sansom OJ, Croucher DR, Parker BL, Pajic M, Morton JP, Cox TR, Timpson P. Vennin C, et al. Among authors: braithwaite aw. Nat Commun. 2019 Aug 12;10(1):3637. doi: 10.1038/s41467-019-10968-6. Nat Commun. 2019. PMID: 31406163 Free PMC article.
p53: more research and more questions.
Braithwaite AW, Prives CL. Braithwaite AW, et al. Cell Death Differ. 2006 Jun;13(6):877-80. doi: 10.1038/sj.cdd.4401938. Cell Death Differ. 2006. PMID: 16708075 No abstract available.
Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis.
Wiles AK, Mehta S, Millier M, Woolley AG, Li K, Parker K, Kazantseva M, Wilson M, Young K, Bowie S, Ray S, Slatter TL, Stamp LK, Hessian PA, Braithwaite AW. Wiles AK, et al. Among authors: braithwaite aw. Arthritis Res Ther. 2023 Apr 15;25(1):62. doi: 10.1186/s13075-023-03040-8. Arthritis Res Ther. 2023. PMID: 37060003 Free PMC article.
Adaptive homeostasis and the p53 isoform network.
Mehta S, Campbell H, Drummond CJ, Li K, Murray K, Slatter T, Bourdon JC, Braithwaite AW. Mehta S, et al. Among authors: braithwaite aw. EMBO Rep. 2021 Dec 6;22(12):e53085. doi: 10.15252/embr.202153085. Epub 2021 Nov 15. EMBO Rep. 2021. PMID: 34779563 Free PMC article. Review.
Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk.
Eiholzer RA, Mehta S, Kazantseva M, Drummond CJ, McKinney C, Young K, Slater D, Morten BC, Avery-Kiejda KA, Lasham A, Fleming N, Morrin HR, Reader K, Royds JA, Landmann M, Petrich S, Reddel R, Huschtscha L, Taha A, Hung NA, Slatter TL, Braithwaite AW. Eiholzer RA, et al. Among authors: braithwaite aw. Cancers (Basel). 2020 Sep 1;12(9):2472. doi: 10.3390/cancers12092472. Cancers (Basel). 2020. PMID: 32882831 Free PMC article.
103 results