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TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein S, Kleine CE, Pieper A, Granzow M, Gautsch S, Himmit M, Kahrmann K, Schierwagen R, Uschner FE, Magdaleno F, Naoum ME, Kristiansen G, Walther T, Bader M, Sauerbruch T, Trebicka J. Klein S, et al. Among authors: kristiansen g. Sci Rep. 2019 Aug 12;9(1):11598. doi: 10.1038/s41598-019-48024-4. Sci Rep. 2019. PMID: 31406138 Free PMC article.
Expression of fatty acid synthase in nonalcoholic fatty liver disease.
Dorn C, Riener MO, Kirovski G, Saugspier M, Steib K, Weiss TS, Gäbele E, Kristiansen G, Hartmann A, Hellerbrand C. Dorn C, et al. Among authors: kristiansen g. Int J Clin Exp Pathol. 2010 Mar 25;3(5):505-14. Int J Clin Exp Pathol. 2010. PMID: 20606731 Free PMC article.
Expression of vasoactive proteins in gastric antral mucosa reflects vascular dysfunction in patients with cirrhosis and portal hypertension.
Trebicka J, Wix C, von Heydebrand M, Hittatiya K, Reiberger T, Klein S, Schierwagen R, Kristiansen G, Peck-Radosavljevic M, Fischer HP, Møller S, Bendtsen F, Krag A, Sauerbruch T. Trebicka J, et al. Among authors: kristiansen g. Liver Int. 2015 Apr;35(4):1393-402. doi: 10.1111/liv.12613. Epub 2014 Jul 5. Liver Int. 2015. PMID: 24912856
Quantification of Liver Fibrosis at T1 and T2 Mapping with Extracellular Volume Fraction MRI: Preclinical Results.
Luetkens JA, Klein S, Träber F, Schmeel FC, Sprinkart AM, Kuetting DLR, Block W, Uschner FE, Schierwagen R, Hittatiya K, Kristiansen G, Gieseke J, Schild HH, Trebicka J, Kukuk GM. Luetkens JA, et al. Among authors: kristiansen g. Radiology. 2018 Sep;288(3):748-754. doi: 10.1148/radiol.2018180051. Epub 2018 Jun 26. Radiology. 2018. PMID: 29944086
The multikinase inhibitor regorafenib decreases angiogenesis and improves portal hypertension.
Uschner FE, Schueller F, Nikolova I, Klein S, Schierwagen R, Magdaleno F, Gröschl S, Loosen S, Ritz T, Roderburg C, Vucur M, Kristiansen G, Lammers T, Luedde T, Trebicka J. Uschner FE, et al. Among authors: kristiansen g. Oncotarget. 2018 Nov 16;9(90):36220-36237. doi: 10.18632/oncotarget.26333. eCollection 2018 Nov 16. Oncotarget. 2018. PMID: 30546838 Free PMC article.
Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis.
Brol MJ, Rösch F, Schierwagen R, Magdaleno F, Uschner FE, Manekeller S, Queck A, Schwarzkopf K, Odenthal M, Drebber U, Thiele M, Lingohr P, Plamper A, Kristiansen G, Lotersztajn S, Krag A, Klein S, Rheinwalt KP, Trebicka J. Brol MJ, et al. Among authors: kristiansen g. Am J Physiol Gastrointest Liver Physiol. 2019 Aug 1;317(2):G182-G194. doi: 10.1152/ajpgi.00361.2018. Epub 2019 Jun 12. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 31188634 Free article.
Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats.
Cremonese C, Schierwagen R, Uschner FE, Torres S, Tyc O, Ortiz C, Schulz M, Queck A, Kristiansen G, Bader M, Sauerbruch T, Weiskirchen R, Walther T, Trebicka J, Klein S. Cremonese C, et al. Among authors: kristiansen g. Int J Mol Sci. 2020 May 7;21(9):3308. doi: 10.3390/ijms21093308. Int J Mol Sci. 2020. PMID: 32392802 Free PMC article.
Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models.
Chang J, Meinke J, Geck M, Hebest M, Böhling N, Dolscheid-Pommerich R, Stoffel-Wagner B, Kristiansen G, Overhaus M, Peyman LO, Klein S, Uschner FE, Brol MJ, Vilz TO, Lingohr P, Kalff JC, Jansen C, Strassburg CP, Wehner S, Trebicka J, Praktiknjo M. Chang J, et al. Among authors: kristiansen g. Front Physiol. 2021 Aug 20;12:720898. doi: 10.3389/fphys.2021.720898. eCollection 2021. Front Physiol. 2021. PMID: 34489738 Free PMC article.
Mitophagy-associated genes PINK1 and PARK2 are independent prognostic markers of survival in papillary renal cell carcinoma and associated with aggressive tumor behavior.
Simon AG, Tolkach Y, Esser LK, Ellinger J, Stöhr C, Ritter M, Wach S, Taubert H, Stephan C, Hartmann A, Kristiansen G, Branchi V, Toma MI. Simon AG, et al. Among authors: kristiansen g. Sci Rep. 2020 Nov 2;10(1):18857. doi: 10.1038/s41598-020-75258-4. Sci Rep. 2020. PMID: 33139776 Free PMC article.
620 results