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Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model.
Exp Hematol. 2019 Sep;77:51-60.e1. doi: 10.1016/j.exphem.2019.08.001. Epub 2019 Aug 9.
Exp Hematol. 2019.
PMID: 31404577
Free article.
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.
Keleku-Lukwete N, Suzuki M, Otsuki A, Tsuchida K, Katayama S, Hayashi M, Naganuma E, Moriguchi T, Tanabe O, Engel JD, Imaizumi M, Yamamoto M.
Keleku-Lukwete N, et al.
Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12169-74. doi: 10.1073/pnas.1509158112. Epub 2015 Sep 14.
Proc Natl Acad Sci U S A. 2015.
PMID: 26371321
Free PMC article.
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An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment.
Keleku-Lukwete N, Suzuki M, Yamamoto M.
Keleku-Lukwete N, et al.
Antioxid Redox Signal. 2018 Dec 10;29(17):1746-1755. doi: 10.1089/ars.2017.7358. Epub 2017 Oct 20.
Antioxid Redox Signal. 2018.
PMID: 28899203
Review.
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Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice.
Keleku-Lukwete N, Suzuki M, Panda H, Otsuki A, Katsuoka F, Saito R, Saigusa D, Uruno A, Yamamoto M.
Keleku-Lukwete N, et al.
Blood Adv. 2019 Apr 23;3(8):1285-1297. doi: 10.1182/bloodadvances.2018017574.
Blood Adv. 2019.
PMID: 31015205
Free PMC article.
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Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.
Tsuchida K, Tsujita T, Hayashi M, Ojima A, Keleku-Lukwete N, Katsuoka F, Otsuki A, Kikuchi H, Oshima Y, Suzuki M, Yamamoto M.
Tsuchida K, et al. Among authors: keleku lukwete n.
Free Radic Biol Med. 2017 Feb;103:236-247. doi: 10.1016/j.freeradbiomed.2016.12.041. Epub 2016 Dec 28.
Free Radic Biol Med. 2017.
PMID: 28039084
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GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis.
Katayama S, Suzuki M, Yamaoka A, Keleku-Lukwete N, Katsuoka F, Otsuki A, Kure S, Engel JD, Yamamoto M.
Katayama S, et al. Among authors: keleku lukwete n.
Blood. 2017 Aug 17;130(7):908-919. doi: 10.1182/blood-2016-12-756767. Epub 2017 Jun 19.
Blood. 2017.
PMID: 28630119
Free article.
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