Hettwer S - Search Results

1

Modulation of Agrin and RhoA Pathways Ameliorates Movement Defects and Synapse Morphology in MYO9A-Depleted Zebrafish.

O'Connor E, Cairns G, Spendiff S, Burns D, Hettwer S, Mäder A, Müller J, Horvath R, Slater C, Roos A, Lochmüller H. O'Connor E, et al. Among authors: hettwer s. Cells. 2019 Aug 7;8(8):848. doi: 10.3390/cells8080848. Cells. 2019. PMID: 31394789 Free PMC article.

2

MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion.

O'Connor E, Phan V, Cordts I, Cairns G, Hettwer S, Cox D, Lochmüller H, Roos A. O'Connor E, et al. Among authors: hettwer s. Hum Mol Genet. 2018 Apr 15;27(8):1434-1446. doi: 10.1093/hmg/ddy054. Hum Mol Genet. 2018. PMID: 29462312 Free PMC article.

3

Modulation of the Acetylcholine Receptor Clustering Pathway Improves Neuromuscular Junction Structure and Muscle Strength in a Mouse Model of Congenital Myasthenic Syndrome.

Spendiff S, Howarth R, McMacken G, Davey T, Quinlan K, O'Connor E, Slater C, Hettwer S, Mäder A, Roos A, Horvath R, Lochmüller H. Spendiff S, et al. Among authors: hettwer s. Front Mol Neurosci. 2020 Dec 17;13:594220. doi: 10.3389/fnmol.2020.594220. eCollection 2020. Front Mol Neurosci. 2020. PMID: 33390901 Free PMC article.

4

The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule.

Daryadel A, Haubitz M, Figueiredo M, Steubl D, Roos M, Mäder A, Hettwer S, Wagner CA. Daryadel A, et al. Among authors: hettwer s. PLoS One. 2016 Jul 5;11(7):e0157905. doi: 10.1371/journal.pone.0157905. eCollection 2016. PLoS One. 2016. PMID: 27380275 Free PMC article.

5

Failed reinnervation in aging skeletal muscle.

Aare S, Spendiff S, Vuda M, Elkrief D, Perez A, Wu Q, Mayaki D, Hussain SN, Hettwer S, Hepple RT. Aare S, et al. Among authors: hettwer s. Skelet Muscle. 2016 Sep 1;6(1):29. doi: 10.1186/s13395-016-0101-y. eCollection 2016. Skelet Muscle. 2016. PMID: 27588166 Free PMC article.

6

Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians.

Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT. Spendiff S, et al. Among authors: hettwer s. J Physiol. 2016 Dec 15;594(24):7361-7379. doi: 10.1113/JP272487. Epub 2016 Oct 23. J Physiol. 2016. PMID: 27619626 Free PMC article.

7

Injection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction.

Hettwer S, Lin S, Kucsera S, Haubitz M, Oliveri F, Fariello RG, Ruegg MA, Vrijbloed JW. Hettwer S, et al. PLoS One. 2014 Feb 10;9(2):e88739. doi: 10.1371/journal.pone.0088739. eCollection 2014. PLoS One. 2014. PMID: 24520420 Free PMC article.

8

Elevated levels of a C-terminal agrin fragment identifies a new subset of sarcopenia patients.

Hettwer S, Dahinden P, Kucsera S, Farina C, Ahmed S, Fariello R, Drey M, Sieber CC, Vrijbloed JW. Hettwer S, et al. Exp Gerontol. 2013 Jan;48(1):69-75. doi: 10.1016/j.exger.2012.03.002. Epub 2012 Mar 11. Exp Gerontol. 2013. PMID: 22433628 Free article.

9

Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy.

Boido M, De Amicis E, Valsecchi V, Trevisan M, Ala U, Ruegg MA, Hettwer S, Vercelli A. Boido M, et al. Among authors: hettwer s. Front Cell Neurosci. 2018 Jan 30;12:17. doi: 10.3389/fncel.2018.00017. eCollection 2018. Front Cell Neurosci. 2018. PMID: 29440993 Free PMC article.

10

Testosterone does not affect agrin cleavage in mobility-limited older men despite improvement in physical function.

Gagliano-Jucá T, Storer TW, Pencina KM, Travison TG, Li Z, Huang G, Hettwer S, Dahinden P, Bhasin S, Basaria S. Gagliano-Jucá T, et al. Among authors: hettwer s. Andrology. 2018 Jan;6(1):29-36. doi: 10.1111/andr.12424. Epub 2017 Sep 26. Andrology. 2018. PMID: 28950424 Free article. Clinical Trial.

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