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WNT inhibition creates a BRCA-like state in Wnt-addicted cancer.
Kaur A, Lim JYS, Sepramaniam S, Patnaik S, Harmston N, Lee MA, Petretto E, Virshup DM, Madan B. Kaur A, et al. Among authors: sepramaniam s. EMBO Mol Med. 2021 Apr 9;13(4):e13349. doi: 10.15252/emmm.202013349. Epub 2021 Mar 4. EMBO Mol Med. 2021. PMID: 33660437 Free PMC article.
Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K. Huang C, et al. Among authors: sepramaniam s. ACS Med Chem Lett. 2019 May 23;10(6):978-984. doi: 10.1021/acsmedchemlett.9b00170. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223458 Free PMC article.
Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors.
Kwiatkowski J, Liu B, Tee DHY, Chen G, Ahmad NHB, Wong YX, Poh ZY, Ang SH, Tan ESW, Ong EH, Nurul Dinie, Poulsen A, Pendharkar V, Sangthongpitag K, Lee MA, Sepramaniam S, Ho SY, Cherian J, Hill J, Keller TH, Hung AW. Kwiatkowski J, et al. Among authors: sepramaniam s. J Med Chem. 2018 May 24;61(10):4386-4396. doi: 10.1021/acs.jmedchem.8b00060. Epub 2018 May 4. J Med Chem. 2018. PMID: 29688013
Correction to "Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3".
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K. Huang C, et al. Among authors: sepramaniam s. ACS Med Chem Lett. 2019 Jul 9;10(8):1240. doi: 10.1021/acsmedchemlett.9b00278. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413812 Free PMC article.
Aquaporins: a promising target for drug development.
Jeyaseelan K, Sepramaniam S, Armugam A, Wintour EM. Jeyaseelan K, et al. Among authors: sepramaniam s. Expert Opin Ther Targets. 2006 Dec;10(6):889-909. doi: 10.1517/14728222.10.6.889. Expert Opin Ther Targets. 2006. PMID: 17105375 Review.
Role of microRNAs in kidney homeostasis and disease.
Chandrasekaran K, Karolina DS, Sepramaniam S, Armugam A, Wintour EM, Bertram JF, Jeyaseelan K. Chandrasekaran K, et al. Among authors: sepramaniam s. Kidney Int. 2012 Apr;81(7):617-27. doi: 10.1038/ki.2011.448. Epub 2012 Jan 11. Kidney Int. 2012. PMID: 22237749 Free article. Review.
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