Oakhill JS - Search Results

1

Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry.

Nelson ME, Parker BL, Burchfield JG, Hoffman NJ, Needham EJ, Cooke KC, Naim T, Sylow L, Ling NX, Francis D, Norris DM, Chaudhuri R, Oakhill JS, Richter EA, Lynch GS, Stöckli J, James DE. Nelson ME, et al. Among authors: oakhill js. EMBO J. 2019 Dec 16;38(24):e102578. doi: 10.15252/embj.2019102578. Epub 2019 Aug 5. EMBO J. 2019. PMID: 31381180 Free PMC article.

2

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.

Dzamko N, Schertzer JD, Ryall JG, Steel R, Macaulay SL, Wee S, Chen ZP, Michell BJ, Oakhill JS, Watt MJ, Jørgensen SB, Lynch GS, Kemp BE, Steinberg GR. Dzamko N, et al. Among authors: oakhill js. J Physiol. 2008 Dec 1;586(23):5819-31. doi: 10.1113/jphysiol.2008.159814. Epub 2008 Oct 9. J Physiol. 2008. PMID: 18845612 Free PMC article.

3

Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation.

Jørgensen SB, Honeyman J, Oakhill JS, Fazakerley D, Stöckli J, Kemp BE, Steinberg GR. Jørgensen SB, et al. Among authors: oakhill js. Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E57-66. doi: 10.1152/ajpendo.90744.2008. Epub 2009 May 12. Am J Physiol Endocrinol Metab. 2009. PMID: 19435854 Free article.

4

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).

Oakhill JS, Chen ZP, Scott JW, Steel R, Castelli LA, Ling N, Macaulay SL, Kemp BE. Oakhill JS, et al. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19237-41. doi: 10.1073/pnas.1009705107. Epub 2010 Oct 25. Proc Natl Acad Sci U S A. 2010. PMID: 20974912 Free PMC article.

5

AMPK is a direct adenylate charge-regulated protein kinase.

Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE. Oakhill JS, et al. Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094. Science. 2011. PMID: 21680840

6

ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.

Scott JW, Oakhill JS, Ling NX, Langendorf CG, Foitzik RC, Kemp BE, Issinger OG. Scott JW, et al. Among authors: oakhill js. Biochem Biophys Res Commun. 2014 Jan 10;443(2):435-40. doi: 10.1016/j.bbrc.2013.11.130. Epub 2013 Dec 8. Biochem Biophys Res Commun. 2014. PMID: 24332941

7

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

Scott JW, Ling N, Issa SM, Dite TA, O'Brien MT, Chen ZP, Galic S, Langendorf CG, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: oakhill js. Chem Biol. 2014 May 22;21(5):619-27. doi: 10.1016/j.chembiol.2014.03.006. Epub 2014 Apr 17. Chem Biol. 2014. PMID: 24746562

8

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE, Kay TW, Birnberg NC, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: oakhill js. Chem Biol. 2015 Jun 18;22(6):705-11. doi: 10.1016/j.chembiol.2015.05.011. Chem Biol. 2015. PMID: 26091167

9

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding.

Langendorf CG, Ngoei KRW, Scott JW, Ling NXY, Issa SMA, Gorman MA, Parker MW, Sakamoto K, Oakhill JS, Kemp BE. Langendorf CG, et al. Among authors: oakhill js. Nat Commun. 2016 Mar 8;7:10912. doi: 10.1038/ncomms10912. Nat Commun. 2016. PMID: 26952388 Free PMC article.

10

β-subunit myristoylation functions as an energy sensor by modulating the dynamics of AMP-activated Protein Kinase.

Ali N, Ling N, Krishnamurthy S, Oakhill JS, Scott JW, Stapleton DI, Kemp BE, Anand GS, Gooley PR. Ali N, et al. Among authors: oakhill js. Sci Rep. 2016 Dec 21;6:39417. doi: 10.1038/srep39417. Sci Rep. 2016. PMID: 28000716 Free PMC article.

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