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In Vivo Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous β-Amyloid Levels.
García-Rojo G, Gámiz F, Ampuero E, Rojas-Espina D, Sandoval R, Rozas C, Morales B, Wyneken U, Pancetti F. García-Rojo G, et al. Among authors: ampuero e. Front Pharmacol. 2017 Jul 25;8:483. doi: 10.3389/fphar.2017.00483. eCollection 2017. Front Pharmacol. 2017. PMID: 28790916 Free PMC article.
Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice.
Bustos FJ, Ampuero E, Jury N, Aguilar R, Falahi F, Toledo J, Ahumada J, Lata J, Cubillos P, Henríquez B, Guerra MV, Stehberg J, Neve RL, Inestrosa NC, Wyneken U, Fuenzalida M, Härtel S, Sena-Esteves M, Varela-Nallar L, Rots MG, Montecino M, van Zundert B. Bustos FJ, et al. Among authors: ampuero e. Brain. 2017 Dec 1;140(12):3252-3268. doi: 10.1093/brain/awx272. Brain. 2017. PMID: 29155979 Free PMC article.
Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice.
Jury N, Abarzua S, Diaz I, Guerra MV, Ampuero E, Cubillos P, Martinez P, Herrera-Soto A, Arredondo C, Rojas F, Manterola M, Rojas A, Montecino M, Varela-Nallar L, van Zundert B. Jury N, et al. Among authors: ampuero e. Clin Epigenetics. 2020 Feb 18;12(1):32. doi: 10.1186/s13148-020-0816-9. Clin Epigenetics. 2020. PMID: 32070418 Free PMC article.
23 results