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Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model.
Mandler M, Rockenstein E, Overk C, Mante M, Florio J, Adame A, Kim C, Santic R, Schneeberger A, Mattner F, Schmidhuber S, Galabova G, Spencer B, Masliah E, Rissman RA. Mandler M, et al. Among authors: schneeberger a. Alzheimers Dement. 2019 Sep;15(9):1133-1148. doi: 10.1016/j.jalz.2019.02.002. Epub 2019 Aug 1. Alzheimers Dement. 2019. PMID: 31378574 Free PMC article.
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy.
Mandler M, Valera E, Rockenstein E, Mante M, Weninger H, Patrick C, Adame A, Schmidhuber S, Santic R, Schneeberger A, Schmidt W, Mattner F, Masliah E. Mandler M, et al. Among authors: schneeberger a. Mol Neurodegener. 2015 Mar 19;10:10. doi: 10.1186/s13024-015-0008-9. Mol Neurodegener. 2015. PMID: 25886309 Free PMC article.
Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials.
Mandler M, Valera E, Rockenstein E, Weninger H, Patrick C, Adame A, Santic R, Meindl S, Vigl B, Smrzka O, Schneeberger A, Mattner F, Masliah E. Mandler M, et al. Among authors: schneeberger a. Acta Neuropathol. 2014;127(6):861-79. doi: 10.1007/s00401-014-1256-4. Epub 2014 Feb 14. Acta Neuropathol. 2014. PMID: 24525765 Free PMC article.
Tailoring the antibody response to aggregated Aß using novel Alzheimer-vaccines.
Mandler M, Santic R, Gruber P, Cinar Y, Pichler D, Funke SA, Willbold D, Schneeberger A, Schmidt W, Mattner F. Mandler M, et al. Among authors: schneeberger a. PLoS One. 2015 Jan 22;10(1):e0115237. doi: 10.1371/journal.pone.0115237. eCollection 2015. PLoS One. 2015. PMID: 25611858 Free PMC article.
Vaccination for Parkinson's disease.
Schneeberger A, Mandler M, Mattner F, Schmidt W. Schneeberger A, et al. Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S11-3. doi: 10.1016/S1353-8020(11)70006-2. Parkinsonism Relat Disord. 2012. PMID: 22166404 Review.
Safety and Tolerability of Active Immunotherapy Targeting α-Synuclein with PD03A in Patients with Early Parkinson's Disease: A Randomized, Placebo-Controlled, Phase 1 Study.
Poewe W, Volc D, Seppi K, Medori R, Lührs P, Kutzelnigg A, Djamshidian A, Thun-Hohenstein C, Meissner WG, Rascol O, Schneeberger A, Staffler G; AFF011 investigators; AFF011 study investigators:; Poewe W, Seppi K, Djamshidian A, deMarzi R, Heim B, Mangesius S, Stolz R, Wachowicz K, Volc D, Thun-Hohenstein C, Riha C, Schneeberger A, Bürger V, Galabova G. Poewe W, et al. Among authors: schneeberger a. J Parkinsons Dis. 2021;11(3):1079-1089. doi: 10.3233/JPD-212594. J Parkinsons Dis. 2021. PMID: 34092654 Free PMC article. Clinical Trial.
188 results