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Exploring the prognostic value of circular RNAs in pancreatic ductal adenocarcinoma using genome-wide expression profiling.
Ørbeck SV, Jakobsen T, García-Rodríguez JL, Burton M, Rasmussen LG, Ewald JD, Fristrup CW, Pfeiffer P, Mortensen MB, Kristensen LS, Detlefsen S. Ørbeck SV, et al. Among authors: garcia rodriguez jl. Pancreatology. 2024 Apr 24:S1424-3903(24)00103-0. doi: 10.1016/j.pan.2024.04.004. Online ahead of print. Pancreatology. 2024. PMID: 38724419 Free article.
Chemical genomics reveals targetable programs of human cancers rooted in pluripotency.
Orlando L, Benoit YD, Reid JC, Nakanishi M, Boyd AL, García-Rodriguez JL, Tanasijevic B, Doyle MS, Luchman A, Restall IJ, Bergin CJ, Masibag AN, Aslostovar L, Di Lu J, Laronde S, Collins TJ, Weiss S, Bhatia M. Orlando L, et al. Among authors: garcia rodriguez jl. Cell Chem Biol. 2023 Jul 20;30(7):780-794.e8. doi: 10.1016/j.chembiol.2023.06.004. Epub 2023 Jun 27. Cell Chem Biol. 2023. PMID: 37379846
circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in small cell lung cancer.
Tolomeo D, Traversa D, Venuto S, Ebbesen KK, García Rodríguez JL, Tamma G, Ranieri M, Simonetti G, Ghetti M, Paganelli M, Visci G, Liso A, Kok K, Muscarella LA, Fabrizio FP, Frassanito MA, Lamanuzzi A, Saltarella I, Solimando AG, Fatica A, Ianniello Z, Marsano RM, Palazzo A, Azzariti A, Longo V, Tommasi S, Galetta D, Catino A, Zito A, Mazza T, Napoli A, Martinelli G, Kjems J, Kristensen LS, Vacca A, Storlazzi CT. Tolomeo D, et al. Among authors: garcia rodriguez jl. Genes Chromosomes Cancer. 2023 Jul;62(7):377-391. doi: 10.1002/gcc.23121. Epub 2023 Jan 23. Genes Chromosomes Cancer. 2023. PMID: 36562080
Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis.
Sáenz de Urturi D, Buqué X, Porteiro B, Folgueira C, Mora A, Delgado TC, Prieto-Fernández E, Olaizola P, Gómez-Santos B, Apodaka-Biguri M, González-Romero F, Nieva-Zuluaga A, Ruiz de Gauna M, Goikoetxea-Usandizaga N, García-Rodríguez JL, Gutierrez de Juan V, Aurrekoetxea I, Montalvo-Romeral V, Novoa EM, Martín-Guerrero I, Varela-Rey M, Bhanot S, Lee R, Banales JM, Syn WK, Sabio G, Martínez-Chantar ML, Nogueiras R, Aspichueta P. Sáenz de Urturi D, et al. Among authors: garcia rodriguez jl. Nat Commun. 2022 Mar 1;13(1):1096. doi: 10.1038/s41467-022-28749-z. Nat Commun. 2022. PMID: 35232994 Free PMC article.
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.
Benoit YD, Mitchell RR, Wang W, Orlando L, Boyd AL, Tanasijevic B, Aslostovar L, Shapovalova Z, Doyle M, Bergin CJ, Vojnits K, Casado FL, Di Lu J, Porras DP, García-Rodriguez JL, Russell J, Zouggar A, Masibag AN, Caba C, Koteva K, Kinthada LK, Patel JS, Andres SN, Magolan J, Collins TJ, Wright GD, Bhatia M. Benoit YD, et al. Among authors: garcia rodriguez jl. Cell Chem Biol. 2021 Oct 21;28(10):1394-1406.e10. doi: 10.1016/j.chembiol.2021.04.014. Epub 2021 May 11. Cell Chem Biol. 2021. PMID: 33979648 Free PMC article.
E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment.
González-Romero F, Mestre D, Aurrekoetxea I, O'Rourke CJ, Andersen JB, Woodhoo A, Tamayo-Caro M, Varela-Rey M, Palomo-Irigoyen M, Gómez-Santos B, de Urturi DS, Núñez-García M, García-Rodríguez JL, Fernández-Ares L, Buqué X, Iglesias-Ara A, Bernales I, De Juan VG, Delgado TC, Goikoetxea-Usandizaga N, Lee R, Bhanot S, Delgado I, Perugorria MJ, Errazti G, Mosteiro L, Gaztambide S, Martinez de la Piscina I, Iruzubieta P, Crespo J, Banales JM, Martínez-Chantar ML, Castaño L, Zubiaga AM, Aspichueta P. González-Romero F, et al. Among authors: garcia rodriguez jl. Cancer Res. 2021 Jun 1;81(11):2874-2887. doi: 10.1158/0008-5472.CAN-20-2052. Epub 2021 Mar 26. Cancer Res. 2021. PMID: 33771899
33 results