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Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment.
Koschorke A, Faraci S, Giani D, Chiodoni C, Iorio E, Canese R, Colombo MP, Lamolinara A, Iezzi M, Ladomery M, Vernieri C, de Braud F, Di Nicola M, Tagliabue E, Castagnoli L, Pupa SM. Koschorke A, et al. Among authors: iezzi m. Cell Oncol (Dordr). 2019 Dec;42(6):815-828. doi: 10.1007/s13402-019-00464-w. Epub 2019 Aug 2. Cell Oncol (Dordr). 2019. PMID: 31376137
A limited autoimmunity to p185neu elicited by DNA and allogeneic cell vaccine hampers the progression of preneoplastic lesions in HER-2/NEU transgenic mice.
Lo Iacono M, Cavallo F, Quaglino E, Rolla S, Iezzi M, Pupa SM, De Giovanni C, Lollini PL, Musiani P, Forni G, Calogero RA. Lo Iacono M, et al. Among authors: iezzi m. Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):351-63. doi: 10.1177/039463200501800217. Int J Immunopathol Pharmacol. 2005. PMID: 15888257 Free article.
Triggering CD40 on endothelial cells contributes to tumor growth.
Chiodoni C, Iezzi M, Guiducci C, Sangaletti S, Alessandrini I, Ratti C, Tiboni F, Musiani P, Granger DN, Colombo MP. Chiodoni C, et al. Among authors: iezzi m. J Exp Med. 2006 Oct 30;203(11):2441-50. doi: 10.1084/jem.20060844. Epub 2006 Oct 16. J Exp Med. 2006. PMID: 17043144 Free PMC article.
The human splice variant Δ16HER2 induces rapid tumor onset in a reporter transgenic mouse.
Marchini C, Gabrielli F, Iezzi M, Zenobi S, Montani M, Pietrella L, Kalogris C, Rossini A, Ciravolo V, Castagnoli L, Tagliabue E, Pupa SM, Musiani P, Monaci P, Menard S, Amici A. Marchini C, et al. Among authors: iezzi m. PLoS One. 2011 Apr 29;6(4):e18727. doi: 10.1371/journal.pone.0018727. PLoS One. 2011. PMID: 21559085 Free PMC article.
Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab.
Castagnoli L, Iezzi M, Ghedini GC, Ciravolo V, Marzano G, Lamolinara A, Zappasodi R, Gasparini P, Campiglio M, Amici A, Chiodoni C, Palladini A, Lollini PL, Triulzi T, Menard S, Nanni P, Tagliabue E, Pupa SM. Castagnoli L, et al. Among authors: iezzi m. Cancer Res. 2014 Nov 1;74(21):6248-59. doi: 10.1158/0008-5472.CAN-14-0983. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164009
183 results