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EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.
Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16997-17006. doi: 10.1073/pnas.1900748116. Epub 2019 Aug 2.
Proc Natl Acad Sci U S A. 2019.
PMID: 31375625
Free PMC article.
Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.
Westerlund I, Shi Y, Toskas K, Fell SM, Li S, Surova O, Södersten E, Kogner P, Nyman U, Schlisio S, Holmberg J.
Westerlund I, et al. Among authors: fell sm.
Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6137-E6146. doi: 10.1073/pnas.1700655114. Epub 2017 Jul 10.
Proc Natl Acad Sci U S A. 2017.
PMID: 28696319
Free PMC article.
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Reply to Mohlin et al.: High levels of EPAS1 are closely associated with key features of low-risk neuroblastoma.
Westerlund I, Shi Y, Toskas K, Fell SM, Li S, Södersten E, Schlisio S, Holmberg J.
Westerlund I, et al. Among authors: fell sm.
Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10859-E10860. doi: 10.1073/pnas.1718429115. Epub 2017 Dec 12.
Proc Natl Acad Sci U S A. 2017.
PMID: 29233947
Free PMC article.
No abstract available.
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Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.
Fell SM, Li S, Wallis K, Kock A, Surova O, Rraklli V, Höfig CS, Li W, Mittag J, Henriksson MA, Kenchappa RS, Holmberg J, Kogner P, Schlisio S.
Fell SM, et al.
Genes Dev. 2017 May 15;31(10):1036-1053. doi: 10.1101/gad.297077.117.
Genes Dev. 2017.
PMID: 28637693
Free PMC article.
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The 1p36 Tumor Suppressor KIF 1Bβ Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis.
Li S, Fell SM, Surova O, Smedler E, Wallis K, Chen ZX, Hellman U, Johnsen JI, Martinsson T, Kenchappa RS, Uhlén P, Kogner P, Schlisio S.
Li S, et al. Among authors: fell sm.
Dev Cell. 2016 Jan 25;36(2):164-78. doi: 10.1016/j.devcel.2015.12.029.
Dev Cell. 2016.
PMID: 26812016
Free article.
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The 2-oxoglutarate analog 3-oxoglutarate decreases normoxic hypoxia-inducible factor-1α in cancer cells, induces cell death, and reduces tumor xenograft growth.
Koivunen P, Fell SM, Lu W, Rabinowitz JD, Kung AL, Schlisio S.
Koivunen P, et al. Among authors: fell sm.
Hypoxia (Auckl). 2016;4:15-27. doi: 10.2147/HP.S96366. Epub 2016 Mar 4.
Hypoxia (Auckl). 2016.
PMID: 27525289
Free PMC article.
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RNA helicase A is a downstream mediator of KIF1Bβ tumor-suppressor function in neuroblastoma.
Chen ZX, Wallis K, Fell SM, Sobrado VR, Hemmer MC, Ramsköld D, Hellman U, Sandberg R, Kenchappa RS, Martinson T, Johnsen JI, Kogner P, Schlisio S.
Chen ZX, et al. Among authors: fell sm.
Cancer Discov. 2014 Apr;4(4):434-51. doi: 10.1158/2159-8290.CD-13-0362. Epub 2014 Jan 27.
Cancer Discov. 2014.
PMID: 24469107
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