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Highly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses.
Rasche A, Lehmann F, König A, Goldmann N, Corman VM, Moreira-Soto A, Geipel A, van Riel D, Vakulenko YA, Sander AL, Niekamp H, Kepper R, Schlegel M, Akoua-Koffi C, Souza BFCD, Sahr F, Olayemi A, Schulze V, Petraityte-Burneikiene R, Kazaks A, Lowjaga KAAT, Geyer J, Kuiken T, Drosten C, Lukashev AN, Fichet-Calvet E, Ulrich RG, Glebe D, Drexler JF. Rasche A, et al. Among authors: glebe d. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17007-17012. doi: 10.1073/pnas.1908072116. Epub 2019 Aug 1. Proc Natl Acad Sci U S A. 2019. PMID: 31371507 Free PMC article.
Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes.
Drexler JF, Geipel A, König A, Corman VM, van Riel D, Leijten LM, Bremer CM, Rasche A, Cottontail VM, Maganga GD, Schlegel M, Müller MA, Adam A, Klose SM, Carneiro AJ, Stöcker A, Franke CR, Gloza-Rausch F, Geyer J, Annan A, Adu-Sarkodie Y, Oppong S, Binger T, Vallo P, Tschapka M, Ulrich RG, Gerlich WH, Leroy E, Kuiken T, Glebe D, Drosten C. Drexler JF, et al. Among authors: glebe d. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16151-6. doi: 10.1073/pnas.1308049110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043818 Free PMC article.
Intracellular accumulation of subviral HBsAg particles and diminished Nrf2 activation in HBV genotype G expressing cells lead to an increased ROI level.
Peiffer KH, Akhras S, Himmelsbach K, Hassemer M, Finkernagel M, Carra G, Nuebling M, Chudy M, Niekamp H, Glebe D, Sarrazin C, Zeuzem S, Hildt E. Peiffer KH, et al. Among authors: glebe d. J Hepatol. 2015 Apr;62(4):791-8. doi: 10.1016/j.jhep.2014.11.028. Epub 2014 Nov 28. J Hepatol. 2015. PMID: 25445396
130 results