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Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.
J Med Chem. 2019 Sep 12;62(17):7976-7997. doi: 10.1021/acs.jmedchem.9b00718. Epub 2019 Aug 14.
J Med Chem. 2019.
PMID: 31365252
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Wilding B, Scharn D, Böse D, Baum A, Santoro V, Chetta P, Schnitzer R, Botesteanu DA, Reiser C, Kornigg S, Knesl P, Hörmann A, Köferle A, Corcokovic M, Lieb S, Scholz G, Bruchhaus J, Spina M, Balla J, Peric-Simov B, Zimmer J, Mitzner S, Fett TN, Beran A, Lamarre L, Gerstberger T, Gerlach D, Bauer M, Bergner A, Schlattl A, Bader G, Treu M, Engelhardt H, Zahn S, Fuchs JE, Zuber J, Ettmayer P, Pearson M, Petronczki M, Kraut N, McConnell DB, Solca F, Neumüller RA.
Wilding B, et al. Among authors: peric simov b.
Nat Cancer. 2022 Jul;3(7):821-836. doi: 10.1038/s43018-022-00412-y. Epub 2022 Jul 26.
Nat Cancer. 2022.
PMID: 35883003
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New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
Zolle IM, Berger ML, Hammerschmidt F, Hahner S, Schirbel A, Peric-Simov B.
Zolle IM, et al. Among authors: peric simov b.
J Med Chem. 2008 Apr 10;51(7):2244-53. doi: 10.1021/jm800012w. Epub 2008 Mar 19.
J Med Chem. 2008.
PMID: 18348518
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Simultaneous separation of the stereoisomers of 1-amino-2-hydroxy and 2-amino-1-hydroxypropane phosphonic acids by stereoselective capillary electrophoresis employing a quinine carbamate type chiral selector.
Lämmerhofer M, Zarbl E, Lindner W, Peric Simov B, Hammerschmidt F.
Lämmerhofer M, et al. Among authors: peric simov b.
Electrophoresis. 2001 Apr;22(6):1182-7. doi: 10.1002/1522-2683()22:6<1182::AID-ELPS1182>3.0.CO;2-O.
Electrophoresis. 2001.
PMID: 11358145
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Direct chemical synthesis of chiral methanol of 98% ee and its conversion to [(2)H1,(3)H]methyl tosylate and [(2)H1,(3)H-methyl]methionine.
Peric Simov B, Wuggenig F, Mereiter K, Andres H, France J, Schnelli P, Hammerschmidt F.
Peric Simov B, et al.
J Am Chem Soc. 2005 Oct 12;127(40):13934-40. doi: 10.1021/ja051568g.
J Am Chem Soc. 2005.
PMID: 16201815
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