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Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders.
Sci Rep. 2019 Jul 29;9(1):10919. doi: 10.1038/s41598-019-47227-z.
Sci Rep. 2019.
PMID: 31358782
Free PMC article.
Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties.
Dent SE, King DP, Osterberg VR, Adams EK, Mackiewicz MR, Weissman TA, Unni VK.
Dent SE, et al.
J Biol Chem. 2022 Feb;298(2):101552. doi: 10.1016/j.jbc.2021.101552. Epub 2021 Dec 30.
J Biol Chem. 2022.
PMID: 34973339
Free PMC article.
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