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A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.
Ooi JD, Jiang JH, Eggenhuizen PJ, Chua LL, van Timmeren M, Loh KL, O'Sullivan KM, Gan PY, Zhong Y, Tsyganov K, Shochet LR, Ryan J, Stegeman CA, Fugger L, Reid HH, Rossjohn J, Heeringa P, Holdsworth SR, Peleg AY, Kitching AR. Ooi JD, et al. Among authors: fugger l. Nat Commun. 2019 Jul 29;10(1):3392. doi: 10.1038/s41467-019-11255-0. Nat Commun. 2019. PMID: 31358739 Free PMC article.
The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN.
Ooi JD, Chang J, O'Sullivan KM, Pedchenko V, Hudson BG, Vandenbark AA, Fugger L, Holdsworth SR, Kitching AR. Ooi JD, et al. Among authors: fugger l. J Am Soc Nephrol. 2013 Feb;24(3):419-31. doi: 10.1681/ASN.2012070705. Epub 2013 Feb 14. J Am Soc Nephrol. 2013. PMID: 23411782 Free PMC article.
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR. Ooi JD, et al. Among authors: fugger l. Nature. 2017 May 11;545(7653):243-247. doi: 10.1038/nature22329. Epub 2017 May 3. Nature. 2017. PMID: 28467828 Free PMC article.
Structural and regulatory diversity shape HLA-C protein expression levels.
Kaur G, Gras S, Mobbs JI, Vivian JP, Cortes A, Barber T, Kuttikkatte SB, Jensen LT, Attfield KE, Dendrou CA, Carrington M, McVean G, Purcell AW, Rossjohn J, Fugger L. Kaur G, et al. Among authors: fugger l. Nat Commun. 2017 Jun 26;8:15924. doi: 10.1038/ncomms15924. Nat Commun. 2017. PMID: 28649982 Free PMC article.
HLA variation and disease.
Dendrou CA, Petersen J, Rossjohn J, Fugger L. Dendrou CA, et al. Among authors: fugger l. Nat Rev Immunol. 2018 May;18(5):325-339. doi: 10.1038/nri.2017.143. Epub 2018 Jan 2. Nat Rev Immunol. 2018. PMID: 29292391 Review.
A functional and structural basis for TCR cross-reactivity in multiple sclerosis.
Lang HL, Jacobsen H, Ikemizu S, Andersson C, Harlos K, Madsen L, Hjorth P, Sondergaard L, Svejgaard A, Wucherpfennig K, Stuart DI, Bell JI, Jones EY, Fugger L. Lang HL, et al. Among authors: fugger l. Nat Immunol. 2002 Oct;3(10):940-3. doi: 10.1038/ni835. Epub 2002 Sep 3. Nat Immunol. 2002. PMID: 12244309
Control of autoimmunity by "epitope theft".
Kranc KR, Taylor AM, Willcox N, Fugger L. Kranc KR, et al. Among authors: fugger l. Trends Mol Med. 2005 Jan;11(1):1-4. doi: 10.1016/j.molmed.2004.11.002. Trends Mol Med. 2005. PMID: 15649815 Review.
185 results