Xu S - Search Results

1

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.

Luo Y, Yang Y, Liu M, Wang D, Wang F, Bi Y, Ji J, Li S, Liu Y, Chen R, Huang H, Wang X, Swidnicka-Siergiejko AK, Janowitz T, Beyaz S, Wang G, Xu S, Bialkowska AB, Luo CK, Pin CL, Liang G, Lu X, Wu M, Shroyer KR, Wolff RA, Plunkett W, Ji B, Li Z, Li E, Li X, Yang VW, Logsdon CD, Abbruzzese JL, Lu W. Luo Y, et al. Among authors: xu s. Gastroenterology. 2019 Nov;157(5):1413-1428.e11. doi: 10.1053/j.gastro.2019.07.030. Epub 2019 Jul 25. Gastroenterology. 2019. PMID: 31352001 Free PMC article.

2

Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis.

Hanel W, Marchenko N, Xu S, Yu SX, Weng W, Moll U. Hanel W, et al. Among authors: xu s. Cell Death Differ. 2013 Jul;20(7):898-909. doi: 10.1038/cdd.2013.17. Epub 2013 Mar 29. Cell Death Differ. 2013. PMID: 23538418 Free PMC article.

3

p63 is a prosurvival factor in the adult mammary gland during post-lactational involution, affecting PI-MECs and ErbB2 tumorigenesis.

Yallowitz AR, Alexandrova EM, Talos F, Xu S, Marchenko ND, Moll UM. Yallowitz AR, et al. Among authors: xu s. Cell Death Differ. 2014 Apr;21(4):645-54. doi: 10.1038/cdd.2013.199. Epub 2014 Jan 17. Cell Death Differ. 2014. PMID: 24440910 Free PMC article.

4

p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo.

Alexandrova EM, Mirza SA, Xu S, Schulz-Heddergott R, Marchenko ND, Moll UM. Alexandrova EM, et al. Among authors: xu s. Cell Death Dis. 2017 Mar 9;8(3):e2661. doi: 10.1038/cddis.2017.80. Cell Death Dis. 2017. PMID: 28277540 Free PMC article.

5

Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment.

Alexandrova EM, Yallowitz AR, Li D, Xu S, Schulz R, Proia DA, Lozano G, Dobbelstein M, Moll UM. Alexandrova EM, et al. Among authors: xu s. Nature. 2015 Jul 16;523(7560):352-6. doi: 10.1038/nature14430. Epub 2015 May 25. Nature. 2015. PMID: 26009011 Free PMC article.

6

Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors.

Vaseva AV, Yallowitz AR, Marchenko ND, Xu S, Moll UM. Vaseva AV, et al. Among authors: xu s. Cell Death Dis. 2011 May 12;2(5):e156. doi: 10.1038/cddis.2011.39. Cell Death Dis. 2011. PMID: 21562588 Free PMC article.

7

Ganetespib synergizes with cyclophosphamide to improve survival of mice with autochthonous tumors in a mutant p53-dependent manner.

Alexandrova EM, Xu S, Moll UM. Alexandrova EM, et al. Among authors: xu s. Cell Death Dis. 2017 Mar 16;8(3):e2683. doi: 10.1038/cddis.2017.108. Cell Death Dis. 2017. PMID: 28300840 Free PMC article.

8

Reduced-nicotine cigarettes increase platelet activation in smokers in vivo: a dilemma in harm reduction.

Girdhar G, Xu S, Bluestein D, Jesty J. Girdhar G, et al. Among authors: xu s. Nicotine Tob Res. 2008 Dec;10(12):1737-44. doi: 10.1080/14622200802443528. Nicotine Tob Res. 2008. PMID: 18982536 Clinical Trial.

9

High-Contrast PET Imaging with [¹⁸F]NT160, a Class-IIa Histone Deacetylase Probe for In Vivo Imaging of Epigenetic Machinery in the Central Nervous System.

Turkman N, Xu S, Huang CH, Eyermann C, Salino J, Khan P. Turkman N, et al. Among authors: xu s. J Med Chem. 2023 Apr 27;66(8):5611-5621. doi: 10.1021/acs.jmedchem.2c02064. Epub 2023 Apr 17. J Med Chem. 2023. PMID: 37068265 Free PMC article.

10

Structure-function studies using deletion mutants identify domains of gC1qR/p33 as potential therapeutic targets for vascular permeability and inflammation.

Ghebrehiwet B, Jesty J, Xu S, Vinayagasundaram R, Vinayagasundaram U, Ji Y, Valentino A, Hosszu KK, Mathew S, Joseph K, Kaplan AP, Peerschke EI. Ghebrehiwet B, et al. Among authors: xu s. Front Immunol. 2011 Nov 1;2:58. doi: 10.3389/fimmu.2011.00058. Front Immunol. 2011. PMID: 22282702 Free PMC article.

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