El-Samad H - Search Results

1

De novo design of bioactive protein switches.

Langan RA, Boyken SE, Ng AH, Samson JA, Dods G, Westbrook AM, Nguyen TH, Lajoie MJ, Chen Z, Berger S, Mulligan VK, Dueber JE, Novak WRP, El-Samad H, Baker D. Langan RA, et al. Nature. 2019 Aug;572(7768):205-210. doi: 10.1038/s41586-019-1432-8. Epub 2019 Jul 24. Nature. 2019. PMID: 31341284 Free PMC article.

2

Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway.

McCullagh E, Seshan A, El-Samad H, Madhani HD. McCullagh E, et al. Nat Cell Biol. 2010 Oct;12(10):954-62. doi: 10.1038/ncb2097. Epub 2010 Sep 19. Nat Cell Biol. 2010. PMID: 20852627 Free PMC article.

3

Conformational biosensors reveal GPCR signalling from endosomes.

Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. Irannejad R, et al. Nature. 2013 Mar 28;495(7442):534-8. doi: 10.1038/nature12000. Epub 2013 Mar 20. Nature. 2013. PMID: 23515162 Free PMC article.

4

Dynamic characterization of growth and gene expression using high-throughput automated flow cytometry.

Zuleta IA, Aranda-Díaz A, Li H, El-Samad H. Zuleta IA, et al. Nat Methods. 2014 Apr;11(4):443-8. doi: 10.1038/nmeth.2879. Epub 2014 Mar 9. Nat Methods. 2014. PMID: 24608180 Free PMC article.

5

Synthetic transcriptional synergy.

Ng AH, El-Samad H. Ng AH, et al. Science. 2019 May 10;364(6440):531-532. doi: 10.1126/science.aax4556. Science. 2019. PMID: 31073055 No abstract available.

6

Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs.

Kundert K, Lucas JE, Watters KE, Fellmann C, Ng AH, Heineike BM, Fitzsimmons CM, Oakes BL, Qu J, Prasad N, Rosenberg OS, Savage DF, El-Samad H, Doudna JA, Kortemme T. Kundert K, et al. Nat Commun. 2019 May 9;10(1):2127. doi: 10.1038/s41467-019-09985-2. Nat Commun. 2019. PMID: 31073154 Free PMC article.

7

Modular and tunable biological feedback control using a de novo protein switch.

Ng AH, Nguyen TH, Gómez-Schiavon M, Dods G, Langan RA, Boyken SE, Samson JA, Waldburger LM, Dueber JE, Baker D, El-Samad H. Ng AH, et al. Nature. 2019 Aug;572(7768):265-269. doi: 10.1038/s41586-019-1425-7. Epub 2019 Jul 24. Nature. 2019. PMID: 31341280

8

Design and Analysis of a Proportional-Integral-Derivative Controller with Biological Molecules.

Chevalier M, Gómez-Schiavon M, Ng AH, El-Samad H. Chevalier M, et al. Cell Syst. 2019 Oct 23;9(4):338-353.e10. doi: 10.1016/j.cels.2019.08.010. Epub 2019 Sep 25. Cell Syst. 2019. PMID: 31563473 Free article.

9

A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells.

Fonseca JP, Bonny AR, Kumar GR, Ng AH, Town J, Wu QC, Aslankoohi E, Chen SY, Dods G, Harrigan P, Osimiri LC, Kistler AL, El-Samad H. Fonseca JP, et al. ACS Synth Biol. 2019 Nov 15;8(11):2593-2606. doi: 10.1021/acssynbio.9b00322. Epub 2019 Nov 5. ACS Synth Biol. 2019. PMID: 31686495

10

Publisher Correction: Modular and tunable biological feedback control using a de novo protein switch.

Ng AH, Nguyen TH, Gómez-Schiavon M, Dods G, Langan RA, Boyken SE, Samson JA, Waldburger LM, Dueber JE, Baker D, El-Samad H. Ng AH, et al. Nature. 2020 Mar;579(7798):E8. doi: 10.1038/s41586-020-2046-x. Nature. 2020. PMID: 32094663

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