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HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules.
Ackermann C, Smits M, Woost R, Eberhard JM, Peine S, Kummer S, Marget M, Kuntzen T, Kwok WW, Lohse AW, Jacobs T, Boettler T, Schulze Zur Wiesch J. Ackermann C, et al. Among authors: schulze zur wiesch j. Sci Rep. 2019 Jul 23;9(1):10624. doi: 10.1038/s41598-019-47024-8. Sci Rep. 2019. PMID: 31337800 Free PMC article.
Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection.
Schulze Zur Wiesch J, Lauer GM, Timm J, Kuntzen T, Neukamm M, Berical A, Jones AM, Nolan BE, Longworth SA, Kasprowicz V, McMahon C, Wurcel A, Lohse AW, Lewis-Ximenez LL, Chung RT, Kim AY, Allen TM, Walker BD. Schulze Zur Wiesch J, et al. Blood. 2007 Sep 1;110(5):1559-69. doi: 10.1182/blood-2007-01-069583. Epub 2007 May 2. Blood. 2007. PMID: 17475911 Free PMC article. Clinical Trial.
Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution.
Timm J, Li B, Daniels MG, Bhattacharya T, Reyor LL, Allgaier R, Kuntzen T, Fischer W, Nolan BE, Duncan J, Schulze zur Wiesch J, Kim AY, Frahm N, Brander C, Chung RT, Lauer GM, Korber BT, Allen TM. Timm J, et al. Among authors: schulze zur wiesch j. Hepatology. 2007 Aug;46(2):339-49. doi: 10.1002/hep.21702. Hepatology. 2007. PMID: 17559151
Viral sequence evolution in acute hepatitis C virus infection.
Kuntzen T, Timm J, Berical A, Lewis-Ximenez LL, Jones A, Nolan B, Schulze zur Wiesch J, Li B, Schneidewind A, Kim AY, Chung RT, Lauer GM, Allen TM. Kuntzen T, et al. Among authors: schulze zur wiesch j. J Virol. 2007 Nov;81(21):11658-68. doi: 10.1128/JVI.00995-07. Epub 2007 Aug 15. J Virol. 2007. PMID: 17699568 Free PMC article.
High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.
Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, Nolan BE, Longworth S, Berical A, Blum J, McMahon C, Reyor LL, Elias N, Kwok WW, McGovern BG, Freeman G, Chung RT, Klenerman P, Lewis-Ximenez L, Walker BD, Allen TM, Kim AY, Lauer GM. Kasprowicz V, et al. Among authors: schulze zur wiesch j. J Virol. 2008 Mar;82(6):3154-60. doi: 10.1128/JVI.02474-07. Epub 2007 Dec 26. J Virol. 2008. PMID: 18160439 Free PMC article.
Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.
Kasprowicz V, Kang YH, Lucas M, Schulze zur Wiesch J, Kuntzen T, Fleming V, Nolan BE, Longworth S, Berical A, Bengsch B, Thimme R, Lewis-Ximenez L, Allen TM, Kim AY, Klenerman P, Lauer GM. Kasprowicz V, et al. Among authors: schulze zur wiesch j. J Virol. 2010 Feb;84(3):1656-63. doi: 10.1128/JVI.01499-09. Epub 2009 Nov 11. J Virol. 2010. PMID: 19906915 Free PMC article.
Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes.
Kim AY, Kuntzen T, Timm J, Nolan BE, Baca MA, Reyor LL, Berical AC, Feller AJ, Johnson KL, Schulze zur Wiesch J, Robbins GK, Chung RT, Walker BD, Carrington M, Allen TM, Lauer GM. Kim AY, et al. Among authors: schulze zur wiesch j. Gastroenterology. 2011 Feb;140(2):686-696.e1. doi: 10.1053/j.gastro.2010.09.042. Epub 2010 Sep 24. Gastroenterology. 2011. PMID: 20875418 Free PMC article.
218 results