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Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells.
Costantini D, Overi D, Casadei L, Cardinale V, Nevi L, Carpino G, Di Matteo S, Safarikia S, Valerio M, Melandro F, Bizzarri M, Manetti C, Berloco PB, Gaudio E, Alvaro D. Costantini D, et al. Among authors: safarikia s. Sci Rep. 2019 Apr 3;9(1):5559. doi: 10.1038/s41598-019-41908-5. Sci Rep. 2019. PMID: 30944365 Free PMC article.
Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD.
Carpino G, Del Ben M, Pastori D, Carnevale R, Baratta F, Overi D, Francis H, Cardinale V, Onori P, Safarikia S, Cammisotto V, Alvaro D, Svegliati-Baroni G, Angelico F, Gaudio E, Violi F. Carpino G, et al. Among authors: safarikia s. Hepatology. 2020 Aug;72(2):470-485. doi: 10.1002/hep.31056. Epub 2020 May 22. Hepatology. 2020. PMID: 31808577
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential.
Cardinale V, Carpino G, Overi D, Safarikia S, Zhang W, Kanke M, Franchitto A, Costantini D, Riccioni O, Nevi L, Chiappetta M, Onori P, Franchitto M, Bini S, Hung YH, Lai Q, Zizzari I, Nuti M, Nicoletti C, Checquolo S, Di Magno L, Giuli MV, Rossi M, Sethupathy P, Reid LM, Alvaro D, Gaudio E. Cardinale V, et al. Among authors: safarikia s. J Hepatol. 2023 Jan;78(1):165-179. doi: 10.1016/j.jhep.2022.08.037. Epub 2022 Sep 9. J Hepatol. 2023. PMID: 36089156
The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma.
Di Matteo S, Nevi L, Costantini D, Overi D, Carpino G, Safarikia S, Giulitti F, Napoletano C, Manzi E, De Rose AM, Melandro F, Bragazzi M, Berloco PB, Giuliante F, Grazi G, Giorgi A, Cardinale V, Adorini L, Gaudio E, Alvaro D. Di Matteo S, et al. Among authors: safarikia s. PLoS One. 2019 Jan 24;14(1):e0210077. doi: 10.1371/journal.pone.0210077. eCollection 2019. PLoS One. 2019. PMID: 30677052 Free PMC article.
Functions and the Emerging Role of the Foetal Liver into Regenerative Medicine.
Giancotti A, Monti M, Nevi L, Safarikia S, D’Ambrosio V, Brunelli R, Pajno C, Corno S, Di Donato V, Musella A, Chiappetta MF, Bosco D, Panici PB, Alvaro D, Cardinale V. Giancotti A, et al. Among authors: safarikia s. Cells. 2019 Aug 16;8(8):914. doi: 10.3390/cells8080914. Cells. 2019. PMID: 31426422 Free PMC article. Review.
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