Glynn SE - Search Results

1

Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease.

Puchades C, Ding B, Song A, Wiseman RL, Lander GC, Glynn SE. Puchades C, et al. Among authors: glynn se. Mol Cell. 2019 Sep 5;75(5):1073-1085.e6. doi: 10.1016/j.molcel.2019.06.016. Epub 2019 Jul 18. Mol Cell. 2019. PMID: 31327635 Free PMC article.

2

Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.

Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC. Puchades C, et al. Among authors: glynn se. Science. 2017 Nov 3;358(6363):eaao0464. doi: 10.1126/science.aao0464. Science. 2017. PMID: 29097521 Free PMC article.

3

Dissecting Substrate Specificities of the Mitochondrial AFG3L2 Protease.

Ding B, Martin DW, Rampello AJ, Glynn SE. Ding B, et al. Among authors: glynn se. Biochemistry. 2018 Jul 17;57(28):4225-4235. doi: 10.1021/acs.biochem.8b00565. Epub 2018 Jul 5. Biochemistry. 2018. PMID: 29932645 Free PMC article.

4

Identification of a Degradation Signal Sequence within Substrates of the Mitochondrial i-AAA Protease.

Rampello AJ, Glynn SE. Rampello AJ, et al. Among authors: glynn se. J Mol Biol. 2017 Mar 24;429(6):873-885. doi: 10.1016/j.jmb.2017.02.009. Epub 2017 Feb 16. J Mol Biol. 2017. PMID: 28214511 Free PMC article.

5

Mitochondrial AAA proteases: A stairway to degradation.

Steele TE, Glynn SE. Steele TE, et al. Among authors: glynn se. Mitochondrion. 2019 Nov;49:121-127. doi: 10.1016/j.mito.2019.07.012. Epub 2019 Aug 1. Mitochondrion. 2019. PMID: 31377246 Free PMC article. Review.

6

Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane.

Shi H, Rampello AJ, Glynn SE. Shi H, et al. Among authors: glynn se. Nat Commun. 2016 Oct 27;7:13301. doi: 10.1038/ncomms13301. Nat Commun. 2016. PMID: 27786171 Free PMC article.

7

Nucleotide binding and conformational switching in the hexameric ring of a AAA+ machine.

Stinson BM, Nager AR, Glynn SE, Schmitz KR, Baker TA, Sauer RT. Stinson BM, et al. Among authors: glynn se. Cell. 2013 Apr 25;153(3):628-39. doi: 10.1016/j.cell.2013.03.029. Cell. 2013. PMID: 23622246 Free PMC article.

8

Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine.

Glynn SE, Martin A, Nager AR, Baker TA, Sauer RT. Glynn SE, et al. Cell. 2009 Nov 13;139(4):744-56. doi: 10.1016/j.cell.2009.09.034. Cell. 2009. PMID: 19914167 Free PMC article.

9

Multifunctional Mitochondrial AAA Proteases.

Glynn SE. Glynn SE. Front Mol Biosci. 2017 May 22;4:34. doi: 10.3389/fmolb.2017.00034. eCollection 2017. Front Mol Biosci. 2017. PMID: 28589125 Free PMC article. Review.

10

Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD.

Li S, Wu Z, Tantray I, Li Y, Chen S, Dong J, Glynn S, Vogel H, Snyder M, Lu B. Li S, et al. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25104-25115. doi: 10.1073/pnas.2005506117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958650 Free PMC article.

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