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Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events.
Guerrini M, Beccati D, Shriver Z, Naggi A, Viswanathan K, Bisio A, Capila I, Lansing JC, Guglieri S, Fraser B, Al-Hakim A, Gunay NS, Zhang Z, Robinson L, Buhse L, Nasr M, Woodcock J, Langer R, Venkataraman G, Linhardt RJ, Casu B, Torri G, Sasisekharan R. Guerrini M, et al. Nat Biotechnol. 2008 Jun;26(6):669-75. doi: 10.1038/nbt1407. Epub 2008 Apr 23. Nat Biotechnol. 2008. PMID: 18437154 Free PMC article.
Orthogonal analytical approaches to detect potential contaminants in heparin.
Guerrini M, Zhang Z, Shriver Z, Naggi A, Masuko S, Langer R, Casu B, Linhardt RJ, Torri G, Sasisekharan R. Guerrini M, et al. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16956-61. doi: 10.1073/pnas.0906861106. Epub 2009 Sep 23. Proc Natl Acad Sci U S A. 2009. PMID: 19805108 Free PMC article.
Multivariate analysis applied to complex biological medicines.
Rudd TR, Mauri L, Marinozzi M, Stancanelli E, Yates EA, Naggi A, Guerrini M. Rudd TR, et al. Among authors: guerrini m. Faraday Discuss. 2019 Aug 15;218(0):303-316. doi: 10.1039/c9fd00009g. Faraday Discuss. 2019. PMID: 31123736
259 results