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Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians.
Bonafè M, Marchegiani F, Cardelli M, Olivieri F, Cavallone L, Giovagnetti S, Pieri C, Marra M, Antonicelli R, Troiano L, Gueresi P, Passeri G, Berardelli M, Paolisso G, Barbieri M, Tesei S, Lisa R, De Benedictis G, Franceschi C. Bonafè M, et al. Among authors: franceschi c. Eur J Hum Genet. 2002 May;10(5):292-6. doi: 10.1038/sj.ejhg.5200806. Eur J Hum Genet. 2002. PMID: 12082503
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes.
Zhang J, Asin-Cayuela J, Fish J, Michikawa Y, Bonafe M, Olivieri F, Passarino G, De Benedictis G, Franceschi C, Attardi G. Zhang J, et al. Among authors: franceschi c. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1116-21. doi: 10.1073/pnas.242719399. Epub 2003 Jan 21. Proc Natl Acad Sci U S A. 2003. PMID: 12538859 Free PMC article.
The role of IL-1 gene cluster in longevity: a study in Italian population.
Cavallone L, Bonafè M, Olivieri F, Cardelli M, Marchegiani F, Giovagnetti S, Di Stasio G, Giampieri C, Mugianesi E, Stecconi R, Sciacca F, Grimaldi LM, De Benedictis G, Lio D, Caruso C, Franceschi C. Cavallone L, et al. Among authors: franceschi c. Mech Ageing Dev. 2003 Apr;124(4):533-8. doi: 10.1016/s0047-6374(03)00033-2. Mech Ageing Dev. 2003. PMID: 12714264
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control.
Bonafè M, Barbieri M, Marchegiani F, Olivieri F, Ragno E, Giampieri C, Mugianesi E, Centurelli M, Franceschi C, Paolisso G. Bonafè M, et al. Among authors: franceschi c. J Clin Endocrinol Metab. 2003 Jul;88(7):3299-304. doi: 10.1210/jc.2002-021810. J Clin Endocrinol Metab. 2003. PMID: 12843179
1,019 results