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Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures.
Nathanson AJ, Zhang Y, Smalley JL, Ollerhead TA, Rodriguez Santos MA, Andrews PM, Wobst HJ, Moore YE, Brandon NJ, Hines RM, Davies PA, Moss SJ. Nathanson AJ, et al. Among authors: brandon nj. Cell Rep. 2019 Jul 16;28(3):670-681.e8. doi: 10.1016/j.celrep.2019.06.014. Cell Rep. 2019. PMID: 31315046 Free PMC article.
KCC2 activity is critical in limiting the onset and severity of status epilepticus.
Silayeva L, Deeb TZ, Hines RM, Kelley MR, Munoz MB, Lee HH, Brandon NJ, Dunlop J, Maguire J, Davies PA, Moss SJ. Silayeva L, et al. Among authors: brandon nj. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3523-8. doi: 10.1073/pnas.1415126112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733865 Free PMC article.
Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders.
Vien TN, Modgil A, Abramian AM, Jurd R, Walker J, Brandon NJ, Terunuma M, Rudolph U, Maguire J, Davies PA, Moss SJ. Vien TN, et al. Among authors: brandon nj. Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14805-10. doi: 10.1073/pnas.1514657112. Epub 2015 Nov 16. Proc Natl Acad Sci U S A. 2015. PMID: 26627235 Free PMC article.
Seizing Control of KCC2: A New Therapeutic Target for Epilepsy.
Moore YE, Kelley MR, Brandon NJ, Deeb TZ, Moss SJ. Moore YE, et al. Among authors: brandon nj. Trends Neurosci. 2017 Sep;40(9):555-571. doi: 10.1016/j.tins.2017.06.008. Epub 2017 Aug 10. Trends Neurosci. 2017. PMID: 28803659 Review.
Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses.
Mukherjee J, Cardarelli RA, Cantaut-Belarif Y, Deeb TZ, Srivastava DP, Tyagarajan SK, Pangalos MN, Triller A, Maguire J, Brandon NJ, Moss SJ. Mukherjee J, et al. Among authors: brandon nj. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11763-11768. doi: 10.1073/pnas.1705075114. Epub 2017 Oct 16. Proc Natl Acad Sci U S A. 2017. PMID: 29078280 Free PMC article.
153 results