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Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer.
Nguyen PM, Dagley LF, Preaudet A, Lam N, Giam M, Fung KY, Aizel K, van Duijneveldt G, Tan CW, Hirokawa Y, Yip HYK, Love CG, Poh AR, Cruz A, Burstroem C, Feltham R, Abdirahman SM, Meiselbach K, Low RRJ, Palmieri M, Ernst M, Webb AI, Burgess T, Sieber OM, Bouillet P, Putoczki TL. Nguyen PM, et al. Among authors: hirokawa y. Cell Death Differ. 2020 Feb;27(2):742-757. doi: 10.1038/s41418-019-0383-9. Epub 2019 Jul 11. Cell Death Differ. 2020. PMID: 31296963 Free PMC article.
Defining the susceptibility of colorectal cancers to BH3-mimetic compounds.
Luo MJ, Palmieri M, Riffkin CD, Sakthianandeswaren A, Djajawi TM, Hirokawa Y, Shuttleworth V, Segal DH, White CA, Nhu D, Lessene G, Lee M, Gibbs P, Huang DCS, Sieber OM, Gong JN. Luo MJ, et al. Among authors: hirokawa y. Cell Death Dis. 2020 Sep 10;11(9):735. doi: 10.1038/s41419-020-02815-0. Cell Death Dis. 2020. PMID: 32913182 Free PMC article.
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Phesse TJ, Buchert M, Stuart E, Flanagan DJ, Faux M, Afshar-Sterle S, Walker F, Zhang HH, Nowell CJ, Jorissen R, Tan CW, Hirokawa Y, Eissmann MF, Poh AR, Malaterre J, Pearson HB, Kirsch DG, Provero P, Poli V, Ramsay RG, Sieber O, Burgess AW, Huszar D, Vincan E, Ernst M. Phesse TJ, et al. Among authors: hirokawa y. Sci Signal. 2014 Sep 30;7(345):ra92. doi: 10.1126/scisignal.2005411. Sci Signal. 2014. PMID: 25270258 Free article.
Colon cryptogenesis: asymmetric budding.
Tan CW, Hirokawa Y, Gardiner BS, Smith DW, Burgess AW. Tan CW, et al. Among authors: hirokawa y. PLoS One. 2013 Oct 21;8(10):e78519. doi: 10.1371/journal.pone.0078519. eCollection 2013. PLoS One. 2013. PMID: 24205248 Free PMC article.
Colonic myofibroblast cell line stimulates colonoid formation.
Hirokawa Y, Yip KH, Tan CW, Burgess AW. Hirokawa Y, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 1;306(7):G547-56. doi: 10.1152/ajpgi.00267.2013. Epub 2014 Jan 30. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24481605 Free article.
A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan CW, Owen A, Hirokawa Y, Gnann A, Orend G, Orner G, Dashwood RH, Heath JK, Ernst M, Janssen KP. Buchert M, et al. Among authors: hirokawa y. Dis Model Mech. 2015 Nov;8(11):1361-73. doi: 10.1242/dmm.019844. Epub 2015 Aug 6. Dis Model Mech. 2015. PMID: 26398937 Free PMC article.
324 results