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Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer.
Nguyen PM, Dagley LF, Preaudet A, Lam N, Giam M, Fung KY, Aizel K, van Duijneveldt G, Tan CW, Hirokawa Y, Yip HYK, Love CG, Poh AR, Cruz A, Burstroem C, Feltham R, Abdirahman SM, Meiselbach K, Low RRJ, Palmieri M, Ernst M, Webb AI, Burgess T, Sieber OM, Bouillet P, Putoczki TL. Nguyen PM, et al. Among authors: feltham r. Cell Death Differ. 2020 Feb;27(2):742-757. doi: 10.1038/s41418-019-0383-9. Epub 2019 Jul 11. Cell Death Differ. 2020. PMID: 31296963 Free PMC article.
SPATA2 - Keeping the TNF signal short and sweet.
Feltham R, Webb AI, Silke J. Feltham R, et al. EMBO J. 2016 Sep 1;35(17):1848-50. doi: 10.15252/embj.201695061. Epub 2016 Jul 28. EMBO J. 2016. PMID: 27470000 Free PMC article.
RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.
Anderton H, Bandala-Sanchez E, Simpson DS, Rickard JA, Ng AP, Di Rago L, Hall C, Vince JE, Silke J, Liccardi G, Feltham R. Anderton H, et al. Among authors: feltham r. Cell Death Differ. 2019 May;26(5):877-889. doi: 10.1038/s41418-018-0166-8. Epub 2018 Sep 5. Cell Death Differ. 2019. PMID: 30185824 Free PMC article.
XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Lawlor KE, Feltham R, Yabal M, Conos SA, Chen KW, Ziehe S, Graß C, Zhan Y, Nguyen TA, Hall C, Vince AJ, Chatfield SM, D'Silva DB, Pang KC, Schroder K, Silke J, Vaux DL, Jost PJ, Vince JE. Lawlor KE, et al. Among authors: feltham r. Cell Rep. 2017 Jul 18;20(3):668-682. doi: 10.1016/j.celrep.2017.06.073. Cell Rep. 2017. PMID: 28723569 Free article.
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P. Liccardi G, et al. Among authors: feltham r. Mol Cell. 2019 Feb 7;73(3):413-428.e7. doi: 10.1016/j.molcel.2018.11.010. Epub 2018 Dec 28. Mol Cell. 2019. PMID: 30598363 Free PMC article.
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J. Vince JE, et al. Among authors: feltham r. Cell. 2007 Nov 16;131(4):682-93. doi: 10.1016/j.cell.2007.10.037. Cell. 2007. PMID: 18022363 Free article.
An Erg-driven transcriptional program controls B cell lymphopoiesis.
Ng AP, Coughlan HD, Hediyeh-Zadeh S, Behrens K, Johanson TM, Low MSY, Bell CC, Gilan O, Chan YC, Kueh AJ, Boudier T, Feltham R, Gabrielyan A, DiRago L, Hyland CD, Ierino H, Mifsud S, Viney E, Willson T, Dawson MA, Allan RS, Herold MJ, Rogers K, Tarlinton DM, Smyth GK, Davis MJ, Nutt SL, Alexander WS. Ng AP, et al. Among authors: feltham r. Nat Commun. 2020 Jun 15;11(1):3013. doi: 10.1038/s41467-020-16828-y. Nat Commun. 2020. PMID: 32541654 Free PMC article.
51 results