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Novel adenosine-derived inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.
J Antibiot (Tokyo). 2019 Dec;72(12):934-942. doi: 10.1038/s41429-019-0199-3. Epub 2019 Jul 12.
J Antibiot (Tokyo). 2019.
PMID: 31296916
Free article.
Mycophenolic Acid and Its Derivatives as Potential Chemotherapeutic Agents Targeting Inosine Monophosphate Dehydrogenase in Trypanosoma congolense.
Suganuma K, Sarwono AE, Mitsuhashi S, Jąkalski M, Okada T, Nthatisi M, Yamagishi J, Ubukata M, Inoue N.
Suganuma K, et al.
Antimicrob Agents Chemother. 2016 Jun 20;60(7):4391-3. doi: 10.1128/AAC.02816-15. Print 2016 Jul.
Antimicrob Agents Chemother. 2016.
PMID: 27139487
Free PMC article.
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Identification and characterization of guanosine 5'-monophosphate reductase of Trypanosoma congolense as a drug target.
Sarwono AEY, Suganuma K, Mitsuhashi S, Okada T, Musinguzi SP, Shigetomi K, Inoue N, Ubukata M.
Sarwono AEY, et al.
Parasitol Int. 2017 Oct;66(5):537-544. doi: 10.1016/j.parint.2017.03.006. Epub 2017 Mar 31.
Parasitol Int. 2017.
PMID: 28366788
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Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening.
Sarwono AEY, Mitsuhashi S, Kabir MHB, Shigetomi K, Okada T, Ohsaka F, Otsuguro S, Maenaka K, Igarashi M, Kato K, Ubukata M.
Sarwono AEY, et al.
J Enzyme Inhib Med Chem. 2019 Dec;34(1):171-178. doi: 10.1080/14756366.2018.1540474.
J Enzyme Inhib Med Chem. 2019.
PMID: 30451014
Free PMC article.
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