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CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury.
Yee C, Main NM, Terry A, Stevanovski I, Maczurek A, Morgan AJ, Calabro S, Potter AJ, Iemma TL, Bowen DG, Ahlenstiel G, Warner FJ, McCaughan GW, McLennan SV, Shackel NA. Yee C, et al. Among authors: main nm. PLoS One. 2019 Jul 10;14(7):e0215557. doi: 10.1371/journal.pone.0215557. eCollection 2019. PLoS One. 2019. PMID: 31291257 Free PMC article.
Targeting the eicosanoid pathway in hepatocellular carcinoma.
Razdan A, Main NM, Chiu V, Shackel NA, de Souza P, Bryant K, Scott KF. Razdan A, et al. Among authors: main nm. Am J Cancer Res. 2021 Jun 15;11(6):2456-2476. eCollection 2021. Am J Cancer Res. 2021. PMID: 34249410 Free PMC article. Review.
SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition.
Lai X, Lui SKL, Lam HY, Adachi Y, Sim WJ, Vasilevski N, Armstrong NJ, Bridgeman SC, Main NM, Tan TZ, Tirnitz-Parker JEE, Thiery JP, Ebi H, Kumar AP, Eichhorn PJA. Lai X, et al. Among authors: main nm. NPJ Precis Oncol. 2023 Dec 15;7(1):136. doi: 10.1038/s41698-023-00486-6. NPJ Precis Oncol. 2023. PMID: 38102334 Free PMC article.