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Page 1
Apoptosis induction by (+)alpha-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells.
Freitas RA, Silva dos Santos GA, Gimenes Teixeira HL, Scheucher PS, Lucena-Araujo AR, Lima AS, Abreu e Lima RS, Garcia AB, Jordão AA Jr, Falcão RP, Vannucchi H, Rego EM. Freitas RA, et al. Among authors: rego em. Leuk Res. 2009 Jul;33(7):958-63. doi: 10.1016/j.leukres.2008.09.035. Epub 2008 Nov 14. Leuk Res. 2009. PMID: 19013639
Interaction of 10-(octyloxy) decyl-2-(trimethylammonium) ethyl phosphate with mimetic membranes and cytotoxic effect on leukemic cells.
dos Santos GA, Thomé CH, Ferreira GA, Yoneda JS, Nobre TM, Daghastanli KR, Scheucher PS, Gimenes-Teixeira HL, Constantino MG, de Oliveira KT, Faça VM, Falcão RP, Greene LJ, Rego EM, Ciancaglini P. dos Santos GA, et al. Among authors: rego em. Biochim Biophys Acta. 2010 Sep;1798(9):1714-23. doi: 10.1016/j.bbamem.2010.05.013. Epub 2010 May 19. Biochim Biophys Acta. 2010. PMID: 20488162 Free article.
(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
dos Santos GA, Abreu e Lima RS, Pestana CR, Lima AS, Scheucher PS, Thomé CH, Gimenes-Teixeira HL, Santana-Lemos BA, Lucena-Araujo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcão RP, de Thé H, Pandolfi PP, Curti C, Rego EM. dos Santos GA, et al. Among authors: rego em. Leukemia. 2012 Mar;26(3):451-60. doi: 10.1038/leu.2011.216. Epub 2011 Aug 26. Leukemia. 2012. PMID: 21869839
Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity.
Thomé CH, dos Santos GA, Ferreira GA, Scheucher PS, Izumi C, Leopoldino AM, Simão AM, Ciancaglini P, de Oliveira KT, Chin A, Hanash SM, Falcão RP, Rego EM, Greene LJ, Faça VM. Thomé CH, et al. Among authors: rego em. Mol Cell Proteomics. 2012 Dec;11(12):1898-912. doi: 10.1074/mcp.M112.019661. Epub 2012 Sep 22. Mol Cell Proteomics. 2012. PMID: 23001822 Free PMC article.
Reversine triggers mitotic catastrophe and apoptosis in K562 cells.
Rodrigues Alves AP, Machado-Neto JA, Scheucher PS, Paiva HH, Simões BP, Rego EM, Traina F. Rodrigues Alves AP, et al. Among authors: rego em. Leuk Res. 2016 Sep;48:26-31. doi: 10.1016/j.leukres.2016.06.011. Epub 2016 Jul 1. Leuk Res. 2016. PMID: 27447890
199 results