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Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin.
Zheng J, Wang J, Wang Q, Zou H, Wang H, Zhang Z, Chen J, Wang Q, Wang P, Zhao Y, Lu J, Zhang X, Xiang S, Wang H, Lei J, Chen HW, Liu P, Liu Y, Han F, Wang J. Zheng J, et al. Among authors: wang h, wang j, wang p, wang q. Acta Pharm Sin B. 2020 Dec;10(12):2313-2322. doi: 10.1016/j.apsb.2020.07.001. Epub 2020 Jul 12. Acta Pharm Sin B. 2020. PMID: 33354503 Free PMC article.
Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma.
Zheng J, Wang Q, Chen J, Cai G, Zhang Z, Zou H, Zou JX, Liu Q, Ji S, Shao G, Li H, Li S, Chen HW, Lu L, Yuan Y, Liu P, Wang J. Zheng J, et al. Among authors: wang j, wang q. Cell Rep Med. 2024 May 21;5(5):101519. doi: 10.1016/j.xcrm.2024.101519. Epub 2024 Apr 30. Cell Rep Med. 2024. PMID: 38692271 Free PMC article.
Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.
Xue X, Zhang Y, Wang C, Zhang M, Xiang Q, Wang J, Wang A, Li C, Zhang C, Zou L, Wang R, Wu S, Lu Y, Chen H, Ding K, Li G, Xu Y. Xue X, et al. Among authors: wang j, wang c, wang r, wang a. Eur J Med Chem. 2018 May 25;152:542-559. doi: 10.1016/j.ejmech.2018.04.034. Epub 2018 Apr 21. Eur J Med Chem. 2018. PMID: 29758518
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