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Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
Baker E, Sims R, Leonenko G, Frizzati A, Harwood JC, Grozeva D; GERAD/PERADES; CHARGE; ADGC; EADI; IGAP consortia; Morgan K, Passmore P, Holmes C, Powell J, Brayne C, Gill M, Mead S, Bossù P, Spalletta G, Goate AM, Cruchaga C, Maier W, Heun R, Jessen F, Peters O, Dichgans M, FröLich L, Ramirez A, Jones L, Hardy J, Ivanov D, Hill M, Holmans P, Allen ND, Morgan BP, Seshadri S, Schellenberg GD, Amouyel P, Williams J, Escott-Price V. Baker E, et al. Among authors: grozeva d. PLoS One. 2019 Jul 8;14(7):e0218111. doi: 10.1371/journal.pone.0218111. eCollection 2019. PLoS One. 2019. PMID: 31283791 Free PMC article.
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N; Wellcome Trust Case Control Consortium. Ferreira MA, et al. Among authors: grozeva d. Nat Genet. 2008 Sep;40(9):1056-8. doi: 10.1038/ng.209. Nat Genet. 2008. PMID: 18711365 Free PMC article.
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.
Craddock N, Jones L, Jones IR, Kirov G, Green EK, Grozeva D, Moskvina V, Nikolov I, Hamshere ML, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Norton N, Breen G, St Clair D, Collier DA, Young AH, Ferrier IN, Farmer A, McGuffin P, Holmans PA; Wellcome Trust Case Control Consortium (WTCCC); Donnelly P, Owen MJ, O'Donovan MC. Craddock N, et al. Among authors: grozeva d. Mol Psychiatry. 2010 Feb;15(2):146-53. doi: 10.1038/mp.2008.66. Epub 2008 Jul 1. Mol Psychiatry. 2010. PMID: 19078961 Free PMC article.
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.
Kirov G, Grozeva D, Norton N, Ivanov D, Mantripragada KK, Holmans P; International Schizophrenia Consortium; Wellcome Trust Case Control Consortium; Craddock N, Owen MJ, O'Donovan MC. Kirov G, et al. Among authors: grozeva d. Hum Mol Genet. 2009 Apr 15;18(8):1497-503. doi: 10.1093/hmg/ddp043. Epub 2009 Jan 29. Hum Mol Genet. 2009. PMID: 19181681 Free PMC article.
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
Hamshere ML, Green EK, Jones IR, Jones L, Moskvina V, Kirov G, Grozeva D, Nikolov I, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Breen G, St Clair D, Collier DA, Young AH, Ferrier IN, Farmer A, McGuffin P; Wellcome Trust Case Control Consortium; Holmans PA, Owen MJ, O'Donovan MC, Craddock N. Hamshere ML, et al. Among authors: grozeva d. Br J Psychiatry. 2009 Jul;195(1):23-9. doi: 10.1192/bjp.bp.108.061424. Br J Psychiatry. 2009. PMID: 19567891 Free PMC article.
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.
Carroll LS, Williams NM, Moskvina V, Russell E, Norton N, Williams HJ, Peirce T, Georgieva L, Dwyer S, Grozeva D, Greene E, Farmer A, McGuffin P, Morris DW, Corvin A, Gill M, Rujescu D, Sham P, Holmans P, Jones I, Kirov G, Craddock N, O'Donovan MC, Owen MJ. Carroll LS, et al. Among authors: grozeva d. Mol Psychiatry. 2010 Nov;15(11):1101-11. doi: 10.1038/mp.2009.96. Epub 2009 Sep 29. Mol Psychiatry. 2010. PMID: 19786960
DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls.
Green EK, Grozeva D, Sims R, Raybould R, Forty L, Gordon-Smith K, Russell E, St Clair D, Young AH, Ferrier IN, Kirov G, Jones I, Jones L, Owen MJ, O'Donovan MC, Craddock N. Green EK, et al. Among authors: grozeva d. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun;156B(4):490-2. doi: 10.1002/ajmg.b.31187. Epub 2011 Mar 28. Am J Med Genet B Neuropsychiatr Genet. 2011. PMID: 21445958
Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms.
Badner JA, Koller D, Foroud T, Edenberg H, Nurnberger JI Jr, Zandi PP, Willour VL, McMahon FJ, Potash JB, Hamshere M, Grozeva D, Green E, Kirov G, Jones I, Jones L, Craddock N, Morris D, Segurado R, Gill M, Sadovnick D, Remick R, Keck P, Kelsoe J, Ayub M, MacLean A, Blackwood D, Liu CY, Gershon ES, McMahon W, Lyon GJ, Robinson R, Ross J, Byerley W. Badner JA, et al. Among authors: grozeva d. Mol Psychiatry. 2012 Jul;17(8):818-26. doi: 10.1038/mp.2011.89. Epub 2011 Jul 19. Mol Psychiatry. 2012. PMID: 21769101 Free PMC article.
129 results