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Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease.
Pettersson M, Johnson DS, Humphrey JM, Am Ende CW, Butler TW, Dorff PH, Efremov IV, Evrard E, Green ME, Helal CJ, Kauffman GW, Mullins PB, Navaratnam T, O'Donnell CJ, O'Sullivan TJ, Patel NC, Stepan AF, Stiff CM, Subramanyam C, Trapa P, Tran TP, Vetelino BC, Yang E, Xie L, Pustilnik LR, Steyn SJ, Wood KM, Bales KR, Hajos-Korcsok E, Verhoest PR. Pettersson M, et al. Among authors: patel nc. J Med Chem. 2024 Jun 7. doi: 10.1021/acs.jmedchem.4c00580. Online ahead of print. J Med Chem. 2024. PMID: 38848667
In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord.
Hanlon KS, Cheng M, Ferrer RM, Ryu JR, Lee B, De La Cruz D, Patel N, Espinoza P, Santoscoy MC, Gong Y, Ng C, Nguyen DM, Nammour J, Clark SW, Heine VM, Sun W, Kozarsky K, Maguire CA. Hanlon KS, et al. Among authors: patel n. Mol Ther. 2024 Jun 5:S1525-0016(24)00382-4. doi: 10.1016/j.ymthe.2024.05.040. Online ahead of print. Mol Ther. 2024. PMID: 38845196
A Two-Year-Old Child with Bilateral Symmetrical Papulosquamous Lesions.
Lakum MP, Padhiyar JK, Patel NH, Patel JR. Lakum MP, et al. Among authors: patel nh. Indian J Dermatol. 2024 Mar-Apr;69(2):198-200. doi: 10.4103/ijd.ijd_347_23. Epub 2024 Apr 29. Indian J Dermatol. 2024. PMID: 38841214 Free PMC article. No abstract available.
The psychosocial impact of prostate cancer screening for BRCA1 and BRCA2 carriers.
Bancroft EK, Page EC, Brook MN, Pope J, Thomas S, Myhill K, Helfand BT, Talaty P, Ong KR, Douglas E, Cook J, Rosario DJ, Salinas M, Buys SS, Anson J, Davidson R, Longmuir M, Side L, Eccles DM, Tischkowitz M, Taylor A, Cruellas M, Ballestero EP, Cleaver R, Varughese M, Barwell J, LeButt M, Greenhalgh L, Hart R, Azzabi A, Jobson I, Cogley L, Evans DG, Rothwell J, Taylor N, Hogben M, Saya S; IMPACT Study Steering Committee; IMPACT Collaborators; Eeles RA, Aaronson NK. Bancroft EK, et al. BJU Int. 2024 Jun 5. doi: 10.1111/bju.16432. Online ahead of print. BJU Int. 2024. PMID: 38839570
9,238 results