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Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species.
Thompson CG, Rosen EP, Prince HMA, White N, Sykes C, de la Cruz G, Mathews M, Deleage C, Estes JD, Charlins P, Mulder LR, Kovarova M, Adamson L, Arora S, Dellon ES, Peery AF, Shaheen NJ, Gay C, Muddiman DC, Akkina R, Garcia JV, Luciw P, Kashuba ADM. Thompson CG, et al. Among authors: adamson l. Sci Transl Med. 2019 Jul 3;11(499):eaap8758. doi: 10.1126/scitranslmed.aap8758. Sci Transl Med. 2019. PMID: 31270274 Free PMC article. Clinical Trial.
Antiretroviral concentrations and surrogate measures of efficacy in the brain tissue and CSF of preclinical species.
Srinivas N, Rosen EP, Gilliland WM Jr, Kovarova M, Remling-Mulder L, De La Cruz G, White N, Adamson L, Schauer AP, Sykes C, Luciw P, Garcia JV, Akkina R, Kashuba ADM. Srinivas N, et al. Among authors: adamson l. Xenobiotica. 2019 Oct;49(10):1192-1201. doi: 10.1080/00498254.2018.1539278. Epub 2018 Dec 17. Xenobiotica. 2019. PMID: 30346892 Free PMC article.
Predicting Efavirenz Concentrations in the Brain Tissue of HIV-Infected Individuals and Exploring their Relationship to Neurocognitive Impairment.
Srinivas N, Joseph SB, Robertson K, Kincer LP, Menezes P, Adamson L, Schauer AP, Blake KH, White N, Sykes C, Luciw P, Eron JJ, Forrest A, Price RW, Spudich S, Swanstrom R, Kashuba ADM. Srinivas N, et al. Among authors: adamson l. Clin Transl Sci. 2019 May;12(3):302-311. doi: 10.1111/cts.12620. Epub 2019 Feb 27. Clin Transl Sci. 2019. PMID: 30675981 Free PMC article. Clinical Trial.
Antiretroviral Drug Concentrations in Lymph Nodes: A Cross-Species Comparison of the Effect of Drug Transporter Expression, Viral Infection, and Sex in Humanized Mice, Nonhuman Primates, and Humans.
Burgunder E, Fallon JK, White N, Schauer AP, Sykes C, Remling-Mulder L, Kovarova M, Adamson L, Luciw P, Garcia JV, Akkina R, Smith PC, Kashuba ADM. Burgunder E, et al. Among authors: adamson l. J Pharmacol Exp Ther. 2019 Sep;370(3):360-368. doi: 10.1124/jpet.119.259150. Epub 2019 Jun 24. J Pharmacol Exp Ther. 2019. PMID: 31235531 Free PMC article.
Antiretroviral Penetration across Three Preclinical Animal Models and Humans in Eight Putative HIV Viral Reservoirs.
Devanathan AS, Pirone JR, Akkina R, Remling-Mulder L, Luciw P, Adamson L, Garcia JV, Kovarova M, White NR, Schauer AP, Blake K, Sykes C, Burgunder EM, Srinivas N, Rosen EP, Kashuba ADM. Devanathan AS, et al. Among authors: adamson l. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01639-19. doi: 10.1128/AAC.01639-19. Print 2019 Dec 20. Antimicrob Agents Chemother. 2019. PMID: 31611355 Free PMC article.
Antiretroviral Penetration and Drug Transporter Concentrations in the Spleens of Three Preclinical Animal Models and Humans.
Devanathan AS, Fallon JK, White NR, Schauer AP, Van Horne B, Blake K, Sykes C, Kovarova M, Adamson L, Remling-Mulder L, Luciw P, Garcia JV, Akkina R, Pirone JR, Smith PC, Kashuba ADM. Devanathan AS, et al. Among authors: adamson l. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e01384-20. doi: 10.1128/AAC.01384-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32661005 Free PMC article.
Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, Reverse Transcriptase Simian-Human Immunodeficiency Virus RNA, and Fibrosis in the Spleens of Nonhuman Primates.
Devanathan AS, White NR, Desyaterik Y, De la Cruz G, Nekorchuk M, Terry M, Busman-Sahay K, Adamson L, Luciw P, Fedoriw Y, Estes JD, Rosen EP, Kashuba ADM. Devanathan AS, et al. Among authors: adamson l. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0060922. doi: 10.1128/aac.00609-22. Epub 2022 Jul 20. Antimicrob Agents Chemother. 2022. PMID: 35856680 Free PMC article.
Multimodal analysis of drug transporter expression in gastrointestinal tissue.
Thompson CG, Fallon JK, Mathews M, Charlins P, Remling-Mulder L, Kovarova M, Adamson L, Srinivas N, Schauer A, Sykes C, Luciw P, Garcia JV, Akkina R, Smith PC, Kashuba ADM. Thompson CG, et al. Among authors: adamson l. AIDS. 2017 Jul 31;31(12):1669-1678. doi: 10.1097/QAD.0000000000001554. AIDS. 2017. PMID: 28590331 Free PMC article.
243 results