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Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes.
Bradford ST, Nair SS, Statham AL, van Dijk SJ, Peters TJ, Anwar F, French HJ, von Martels JZH, Sutcliffe B, Maddugoda MP, Peranec M, Varinli H, Arnoldy R, Buckley M, Ross JP, Zotenko E, Song JZ, Stirzaker C, Bauer DC, Qu W, Swarbrick MM, Lutgers HL, Lord RV, Samaras K, Molloy PL, Clark SJ. Bradford ST, et al. Among authors: maddugoda mp. Sci Rep. 2019 Jul 2;9(1):9511. doi: 10.1038/s41598-019-45777-w. Sci Rep. 2019. PMID: 31266983 Free PMC article.
NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.
Coombs JR, Zamoshnikova A, Holley CL, Maddugoda MP, Teo DET, Chauvin C, Poulin LF, Vitak N, Ross CM, Mellacheruvu M, Coll RC, Heinz LX, Burgener SS, Emming S, Chamaillard M, Boucher D, Schroder K. Coombs JR, et al. Among authors: maddugoda mp. Sci Signal. 2024 Jan 23;17(820):eabg8145. doi: 10.1126/scisignal.abg8145. Epub 2024 Jan 23. Sci Signal. 2024. PMID: 38261657
Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation.
Stefani C, Gonzalez-Rodriguez D, Senju Y, Doye A, Efimova N, Janel S, Lipuma J, Tsai MC, Hamaoui D, Maddugoda MP, Cochet-Escartin O, Prévost C, Lafont F, Svitkina T, Lappalainen P, Bassereau P, Lemichez E. Stefani C, et al. Among authors: maddugoda mp. Nat Commun. 2017 Jun 23;8:15839. doi: 10.1038/ncomms15839. Nat Commun. 2017. PMID: 28643776 Free PMC article.
Cellular dewetting: opening of macroapertures in endothelial cells.
Gonzalez-Rodriguez D, Maddugoda MP, Stefani C, Janel S, Lafont F, Cuvelier D, Lemichez E, Brochard-Wyart F. Gonzalez-Rodriguez D, et al. Among authors: maddugoda mp. Phys Rev Lett. 2012 May 25;108(21):218105. doi: 10.1103/PhysRevLett.108.218105. Epub 2012 May 25. Phys Rev Lett. 2012. PMID: 23003307
cAMP signaling by anthrax edema toxin induces transendothelial cell tunnels, which are resealed by MIM via Arp2/3-driven actin polymerization.
Maddugoda MP, Stefani C, Gonzalez-Rodriguez D, Saarikangas J, Torrino S, Janel S, Munro P, Doye A, Prodon F, Aurrand-Lions M, Goossens PL, Lafont F, Bassereau P, Lappalainen P, Brochard F, Lemichez E. Maddugoda MP, et al. Cell Host Microbe. 2011 Nov 17;10(5):464-74. doi: 10.1016/j.chom.2011.09.014. Cell Host Microbe. 2011. PMID: 22100162 Free article.
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