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Arsenic exposure induces glucose intolerance and alters global energy metabolism.
Kirkley AG, Carmean CM, Ruiz D, Ye H, Regnier SM, Poudel A, Hara M, Kamau W, Johnson DN, Roberts AA, Parsons PJ, Seino S, Sargis RM. Kirkley AG, et al. Among authors: seino s. Am J Physiol Regul Integr Comp Physiol. 2018 Feb 1;314(2):R294-R303. doi: 10.1152/ajpregu.00522.2016. Epub 2017 Nov 14. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 29118024 Free PMC article.
Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells.
Carmean CM, Yokoi N, Takahashi H, Oduori OS, Kang C, Kanagawa A, Kirkley AG, Han G, Landeche M, Hidaka S, Katoh M, Sargis RM, Seino S. Carmean CM, et al. Among authors: seino s. Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E464-E474. doi: 10.1152/ajpendo.00302.2018. Epub 2018 Dec 18. Am J Physiol Endocrinol Metab. 2019. PMID: 30562058 Free PMC article.
DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.
Shimizu S, Hosooka T, Matsuda T, Asahara S, Koyanagi-Kimura M, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K, Takahashi H, Inoue H, Mieda Y, Hashimoto N, Seino S, Kido Y. Shimizu S, et al. Among authors: seino s. J Mol Endocrinol. 2012 Aug 30;49(2):125-35. doi: 10.1530/JME-12-0039. Print 2012 Oct. J Mol Endocrinol. 2012. PMID: 22822047
Cephalic phase insulin secretion is KATP channel independent.
Seino Y, Miki T, Fujimoto W, Young Lee E, Takahashi Y, Minami K, Oiso Y, Seino S. Seino Y, et al. Among authors: seino s. J Endocrinol. 2013 May 28;218(1):25-33. doi: 10.1530/JOE-12-0579. Print 2013 Jul. J Endocrinol. 2013. PMID: 23608222
KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state.
Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. Ogata H, et al. Among authors: seino y, seino s. J Endocrinol. 2014 Aug;222(2):191-200. doi: 10.1530/JOE-14-0161. Epub 2014 Jun 2. J Endocrinol. 2014. PMID: 24891433
633 results