Koomen JM - Search Results

1

Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets.

Sumi NJ, Ctortecka C, Hu Q, Bryant AT, Fang B, Remsing Rix LL, Ayaz M, Kinose F, Welsh EA, Eschrich SA, Lawrence HR, Koomen JM, Haura EB, Rix U. Sumi NJ, et al. Among authors: koomen jm. Cell Chem Biol. 2019 Sep 19;26(9):1240-1252.e11. doi: 10.1016/j.chembiol.2019.06.003. Epub 2019 Jun 27. Cell Chem Biol. 2019. PMID: 31257184 Free PMC article.

2

Proteomic contributions to personalized cancer care.

Koomen JM, Haura EB, Bepler G, Sutphen R, Remily-Wood ER, Benson K, Hussein M, Hazlehurst LA, Yeatman TJ, Hildreth LT, Sellers TA, Jacobsen PB, Fenstermacher DA, Dalton WS. Koomen JM, et al. Mol Cell Proteomics. 2008 Oct;7(10):1780-94. doi: 10.1074/mcp.R800002-MCP200. Epub 2008 Jul 29. Mol Cell Proteomics. 2008. PMID: 18664563 Free PMC article. Review.

3

IPEP: an in silico tool to examine proteolytic peptides for mass spectrometry.

Lu D, Liu RZ, Izumi V, Fenstermacher D, Haura EB, Koomen J, Eschrich SA. Lu D, et al. Bioinformatics. 2008 Dec 1;24(23):2801-2. doi: 10.1093/bioinformatics/btn511. Epub 2008 Oct 7. Bioinformatics. 2008. PMID: 18842605

4

Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat.

Kahali S, Sarcar B, Fang B, Williams ES, Koomen JM, Tofilon PJ, Chinnaiyan P. Kahali S, et al. Among authors: koomen jm. Neoplasia. 2010 Jan;12(1):80-6. doi: 10.1593/neo.91422. Neoplasia. 2010. PMID: 20072656 Free PMC article.

5

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer.

Li J, Rix U, Fang B, Bai Y, Edwards A, Colinge J, Bennett KL, Gao J, Song L, Eschrich S, Superti-Furga G, Koomen J, Haura EB. Li J, et al. Nat Chem Biol. 2010 Apr;6(4):291-9. doi: 10.1038/nchembio.332. Epub 2010 Feb 28. Nat Chem Biol. 2010. PMID: 20190765 Free PMC article.

6

Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation.

Mahajan K, Coppola D, Challa S, Fang B, Chen YA, Zhu W, Lopez AS, Koomen J, Engelman RW, Rivera C, Muraoka-Cook RS, Cheng JQ, Schönbrunn E, Sebti SM, Earp HS, Mahajan NP. Mahajan K, et al. PLoS One. 2010 Mar 19;5(3):e9646. doi: 10.1371/journal.pone.0009646. PLoS One. 2010. PMID: 20333297 Free PMC article.

7

Methods for investigation of targeted kinase inhibitor therapy using chemical proteomics and phosphorylation profiling.

Fang B, Haura EB, Smalley KS, Eschrich SA, Koomen JM. Fang B, et al. Among authors: koomen jm. Biochem Pharmacol. 2010 Sep 1;80(5):739-47. doi: 10.1016/j.bcp.2010.03.027. Epub 2010 Mar 31. Biochem Pharmacol. 2010. PMID: 20361944 Free PMC article. Review.

8

Quantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry.

Chen Y, Gruidl M, Remily-Wood E, Liu RZ, Eschrich S, Lloyd M, Nasir A, Bui MM, Huang E, Shibata D, Yeatman T, Koomen JM. Chen Y, et al. Among authors: koomen jm. J Proteome Res. 2010 Aug 6;9(8):4215-27. doi: 10.1021/pr1005197. J Proteome Res. 2010. PMID: 20590165 Free PMC article.

9

Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling.

Machida K, Eschrich S, Li J, Bai Y, Koomen J, Mayer BJ, Haura EB. Machida K, et al. PLoS One. 2010 Oct 19;5(10):e13470. doi: 10.1371/journal.pone.0013470. PLoS One. 2010. PMID: 20976048 Free PMC article.

10

Mass spectrometry mapping of epidermal growth factor receptor phosphorylation related to oncogenic mutations and tyrosine kinase inhibitor sensitivity.

Zhang G, Fang B, Liu RZ, Lin H, Kinose F, Bai Y, Oguz U, Remily-Wood ER, Li J, Altiok S, Eschrich S, Koomen J, Haura EB. Zhang G, et al. J Proteome Res. 2011 Jan 7;10(1):305-19. doi: 10.1021/pr1006203. Epub 2010 Dec 3. J Proteome Res. 2011. PMID: 21080693 Free PMC article.

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