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Spatial genome exploration in the context of cognitive and neurological disease.
Rajarajan P, Borrman T, Liao W, Espeso-Gil S, Chandrasekaran S, Jiang Y, Weng Z, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: brennand kj. Curr Opin Neurobiol. 2019 Dec;59:112-119. doi: 10.1016/j.conb.2019.05.007. Epub 2019 Jun 27. Curr Opin Neurobiol. 2019. PMID: 31255842 Free PMC article. Review.
Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder.
Mishra HK, Wei H, Rohr KE, Ko I, Nievergelt CM, Maihofer AX, Shilling PD, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Frye M, Gage F, Gershon E, McInnis MG, Nurnberger J, Oedegaard KJ, Zandi PP, Kelsoe JR, McCarthy MJ. Mishra HK, et al. Among authors: brennand kj. Eur Neuropsychopharmacol. 2023 Sep;74:1-14. doi: 10.1016/j.euroneuro.2023.04.009. Epub 2023 Apr 29. Eur Neuropsychopharmacol. 2023. PMID: 37126998
A role for noncoding variation in schizophrenia.
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P. Roussos P, et al. Among authors: brennand kj. Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016/j.celrep.2014.10.015. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25453756 Free PMC article.
Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.
Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, Aronow B, Fang G, Zhang B, Cotter D, Brennand KJ. Topol A, et al. Among authors: brennand kj. Transl Psychiatry. 2015 Oct 20;5(10):e662. doi: 10.1038/tp.2015.118. Transl Psychiatry. 2015. PMID: 26485546 Free PMC article.
Spatial genome organization and cognition.
Rajarajan P, Gil SE, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: brennand kj. Nat Rev Neurosci. 2016 Nov;17(11):681-691. doi: 10.1038/nrn.2016.124. Epub 2016 Oct 6. Nat Rev Neurosci. 2016. PMID: 27708356 Free PMC article. Review.
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Mitchell AC, Javidfar B, Pothula V, Ibi D, Shen EY, Peter CJ, Bicks LK, Fehr T, Jiang Y, Brennand KJ, Neve RL, Gonzalez-Maeso J, Akbarian S. Mitchell AC, et al. Among authors: brennand kj. Mol Psychiatry. 2018 Jan;23(1):123-132. doi: 10.1038/mp.2016.254. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115742 Free PMC article.
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H, Roussos P, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S. Jiang Y, et al. Among authors: brennand kj. Nat Genet. 2017 Aug;49(8):1239-1250. doi: 10.1038/ng.3906. Epub 2017 Jul 3. Nat Genet. 2017. PMID: 28671686 Free PMC article.
151 results