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Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells.
de Matos AM, Martins A, Man T, Evans D, Walter M, Oliveira MC, López Ó, Fernandez-Bolaños JG, Dätwyler P, Ernst B, Macedo MP, Contino M, Colabufo NA, Rauter AP. de Matos AM, et al. Among authors: evans d. Pharmaceuticals (Basel). 2019 Jun 21;12(2):98. doi: 10.3390/ph12020098. Pharmaceuticals (Basel). 2019. PMID: 31234364 Free PMC article.
Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo-PrPC binding and downstream pathways.
Grayson JD, Baumgartner MP, Santos Souza CD, Dawes SJ, El Idrissi IG, Louth JC, Stimpson S, Mead E, Dunbar C, Wolak J, Sharman G, Evans D, Zhuravleva A, Roldan MS, Colabufo NA, Ning K, Garwood C, Thomas JA, Partridge BM, de la Vega de Leon A, Gillet VJ, Rauter AP, Chen B. Grayson JD, et al. Among authors: evans d. Chem Sci. 2021 Feb 1;12(10):3768-3785. doi: 10.1039/d0sc04769d. Chem Sci. 2021. PMID: 34163650 Free PMC article.
Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M₁ agonists.
Liu B, Croy CH, Hitchcock SA, Allen JR, Rao Z, Evans D, Bures MG, McKinzie DL, Watt ML, Stuart Gregory G, Hansen MM, Hoogestraat PJ, Jamison JA, Okha-Mokube FM, Stratford RE, Turner W, Bymaster F, Felder CC. Liu B, et al. Among authors: evans d. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4158-63. doi: 10.1016/j.bmcl.2015.08.011. Epub 2015 Aug 8. Bioorg Med Chem Lett. 2015. PMID: 26299349
Discovery of selective RIO2 kinase small molecule ligand.
Varin T, Godfrey AG, Masquelin T, Nicolaou CA, Evans DA, Vieth M. Varin T, et al. Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1630-6. doi: 10.1016/j.bbapap.2015.04.006. Epub 2015 Apr 17. Biochim Biophys Acta. 2015. PMID: 25891899
8,993 results