Ganapathy S - Search Results

1

Mu-KRAS attenuates Hippo signaling pathway through PKCι to sustain the growth of pancreatic cancer.

Wang P, Zhang H, Yang J, Li Z, Wang Y, Leng X, Ganapathy S, Isakson P, Chen C, Zhu T. Wang P, et al. Among authors: ganapathy s. J Cell Physiol. 2020 Jan;235(1):408-420. doi: 10.1002/jcp.28981. Epub 2019 Jun 23. J Cell Physiol. 2020. PMID: 31230347

2

Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells.

Ganapathy S, Peng B, Shen L, Yu T, Lafontant J, Li P, Xiong R, Makriyannis A, Chen C. Ganapathy S, et al. Oncotarget. 2017 May 9;8(19):30992-31002. doi: 10.18632/oncotarget.16047. Oncotarget. 2017. PMID: 28415683 Free PMC article.

3

PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis.

Wang P, Wei D, Zhang H, Chen J, Zhang D, Ganapathy S, Isakson P, Chen C, Zhu T. Wang P, et al. Among authors: ganapathy s. Oncotarget. 2018 Aug 28;9(67):32736-32750. doi: 10.18632/oncotarget.25127. eCollection 2018 Aug 28. Oncotarget. 2018. PMID: 30214681 Free PMC article.

4

Targeting Bcl-2 stability to sensitize cells harboring oncogenic ras.

Peng B, Ganapathy S, Shen L, Huang J, Yi B, Zhou X, Dai W, Chen C. Peng B, et al. Among authors: ganapathy s. Oncotarget. 2015 Sep 8;6(26):22328-37. doi: 10.18632/oncotarget.4084. Oncotarget. 2015. PMID: 26041886 Free PMC article.

5

PKC is an indispensable factor in promoting environmental toxin chromium-mediated transformation and drug resistance.

Ganapathy S, Liu J, Yu T, Xiong R, Zhang Q, Makriyannis A, Chen C. Ganapathy S, et al. Aging (Albany NY). 2022 Feb 24;14(4):1678-1690. doi: 10.18632/aging.203917. Epub 2022 Feb 24. Aging (Albany NY). 2022. PMID: 35210368 Free PMC article.

6

Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C.

Ganapathy S, Fagman JB, Shen L, Yu T, Zhou X, Dai W, Makriyannis A, Chen C. Ganapathy S, et al. Oncotarget. 2016 Dec 20;7(51):84326-84337. doi: 10.18632/oncotarget.12607. Oncotarget. 2016. PMID: 27741517 Free PMC article.

7

Chromium IV exposure, via Src/Ras signaling, promotes cell transformation.

Ganapathy S, Li P, Lafontant J, Xiong R, Yu T, Zhang G, Chen C. Ganapathy S, et al. Mol Carcinog. 2017 Jul;56(7):1808-1815. doi: 10.1002/mc.22639. Epub 2017 Mar 10. Mol Carcinog. 2017. PMID: 28218450

8

Low doses of arsenic, via perturbing p53, promotes tumorigenesis.

Ganapathy S, Li P, Fagman J, Yu T, Lafontant J, Zhang G, Chen C. Ganapathy S, et al. Toxicol Appl Pharmacol. 2016 Sep 1;306:98-104. doi: 10.1016/j.taap.2016.07.009. Epub 2016 Jul 15. Toxicol Appl Pharmacol. 2016. PMID: 27425828

9

Chronic low dose arsenic exposure preferentially perturbs mitotic phase of the cell cycle.

Ganapathy S, Liu J, Xiong R, Yu T, Makriyannis A, Chen C. Ganapathy S, et al. Genes Cancer. 2019 Feb;10(1-2):39-51. doi: 10.18632/genesandcancer.185. Genes Cancer. 2019. PMID: 30899418 Free PMC article.

10

Nicotine exposure potentiates lung tumorigenesis by perturbing cellular surveillance.

Zhang Q, Ganapathy S, Avraham H, Nishioka T, Chen C. Zhang Q, et al. Among authors: ganapathy s. Br J Cancer. 2020 Mar;122(6):904-911. doi: 10.1038/s41416-020-0730-0. Epub 2020 Jan 31. Br J Cancer. 2020. PMID: 32001831 Free PMC article.

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