Lejeune FX - Search Results

1

Genetic cooperativity in multi-layer networks implicates cell survival and senescence in the striatum of Huntington's disease mice synchronous to symptoms.

Bigan E, Sasidharan Nair S, Lejeune FX, Fragnaud H, Parmentier F, Mégret L, Verny M, Aaronson J, Rosinski J, Neri C. Bigan E, et al. Among authors: lejeune fx. Bioinformatics. 2020 Jan 1;36(1):186-196. doi: 10.1093/bioinformatics/btz514. Bioinformatics. 2020. PMID: 31228193 Free PMC article.

2

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.

Lejeune FX, Mesrob L, Parmentier F, Bicep C, Vazquez-Manrique RP, Parker JA, Vert JP, Tourette C, Neri C. Lejeune FX, et al. BMC Genomics. 2012 Mar 13;13:91. doi: 10.1186/1471-2164-13-91. BMC Genomics. 2012. PMID: 22413862 Free PMC article.

3

Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence.

Parmentier F, Lejeune FX, Neri C. Parmentier F, et al. Among authors: lejeune fx. Front Aging Neurosci. 2013 Jun 13;5:22. doi: 10.3389/fnagi.2013.00022. eCollection 2013. Front Aging Neurosci. 2013. PMID: 23781200 Free PMC article.

4

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.

Achour M, Le Gras S, Keime C, Parmentier F, Lejeune FX, Boutillier AL, Néri C, Davidson I, Merienne K. Achour M, et al. Among authors: lejeune fx. Hum Mol Genet. 2015 Jun 15;24(12):3481-96. doi: 10.1093/hmg/ddv099. Epub 2015 Mar 17. Hum Mol Genet. 2015. PMID: 25784504

5

The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease.

Farina F, Lambert E, Commeau L, Lejeune FX, Roudier N, Fonte C, Parker JA, Boddaert J, Verny M, Baulieu EE, Neri C. Farina F, et al. Among authors: lejeune fx. Sci Rep. 2017 Jun 21;7(1):4014. doi: 10.1038/s41598-017-04256-w. Sci Rep. 2017. PMID: 28638078 Free PMC article.

6

FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16^INK4a increase.

Voisin J, Farina F, Naphade S, Fontaine M, Tshilenge KT, Galicia Aguirre C, Lopez-Ramirez A, Dancourt J, Ginisty A, Sasidharan Nair S, Lakshika Madushani K, Zhang N, Lejeune FX, Verny M, Campisi J, Ellerby LM, Neri C. Voisin J, et al. Among authors: lejeune fx. Aging Cell. 2020 Nov;19(11):e13226. doi: 10.1111/acel.13226. Epub 2020 Nov 6. Aging Cell. 2020. PMID: 33156570 Free PMC article.

7

Propensity for somatic expansion increases over the course of life in Huntington disease.

Kacher R, Lejeune FX, Noël S, Cazeneuve C, Brice A, Humbert S, Durr A. Kacher R, et al. Among authors: lejeune fx. Elife. 2021 May 13;10:e64674. doi: 10.7554/eLife.64674. Elife. 2021. PMID: 33983118 Free PMC article.

8

AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice.

Besse A, Astord S, Marais T, Roda M, Giroux B, Lejeune FX, Relaix F, Smeriglio P, Barkats M, Biferi MG. Besse A, et al. Among authors: lejeune fx. Mol Ther. 2020 Aug 5;28(8):1887-1901. doi: 10.1016/j.ymthe.2020.05.011. Epub 2020 May 15. Mol Ther. 2020. PMID: 32470325 Free PMC article.

9

A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1.

Marie-Claire C, Lejeune FX, Mundwiller E, Ulveling D, Moszer I, Bellivier F, Etain B. Marie-Claire C, et al. Among authors: lejeune fx. Sci Rep. 2020 Jul 22;10(1):12239. doi: 10.1038/s41598-020-69073-0. Sci Rep. 2020. PMID: 32699220 Free PMC article.

10

Somatostatin 1.1 contributes to the innate exploration of zebrafish larva.

Quan FB, Desban L, Mirat O, Kermarquer M, Roussel J, Koëth F, Marnas H, Djenoune L, Lejeune FX, Tostivint H, Wyart C. Quan FB, et al. Among authors: lejeune fx. Sci Rep. 2020 Sep 17;10(1):15235. doi: 10.1038/s41598-020-72039-x. Sci Rep. 2020. PMID: 32943676 Free PMC article.

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