Tholander F - Search Results

1

Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase.

Berggren G, Sahlin M, Crona M, Tholander F, Sjöberg BM. Berggren G, et al. Among authors: tholander f. J Biol Inorg Chem. 2019 Sep;24(6):841-848. doi: 10.1007/s00775-019-01679-w. Epub 2019 Jun 20. J Biol Inorg Chem. 2019. PMID: 31218442 Free PMC article.

2

Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format.

Tholander F, Sjöberg BM. Tholander F, et al. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9798-803. doi: 10.1073/pnas.1113051109. Epub 2012 Jun 4. Proc Natl Acad Sci U S A. 2012. PMID: 22665797 Free PMC article.

3

Biochemical Characterization of the Split Class II Ribonucleotide Reductase from Pseudomonas aeruginosa.

Crona M, Hofer A, Astorga-Wells J, Sjöberg BM, Tholander F. Crona M, et al. Among authors: tholander f. PLoS One. 2015 Jul 30;10(7):e0134293. doi: 10.1371/journal.pone.0134293. eCollection 2015. PLoS One. 2015. PMID: 26225432 Free PMC article.

4

The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.

Aurelius O, Johansson R, Bågenholm V, Lundin D, Tholander F, Balhuizen A, Beck T, Sahlin M, Sjöberg BM, Mulliez E, Logan DT. Aurelius O, et al. Among authors: tholander f. PLoS One. 2015 Jul 6;10(7):e0128199. doi: 10.1371/journal.pone.0128199. eCollection 2015. PLoS One. 2015. PMID: 26147435 Free PMC article.

5

A ribonucleotide reductase inhibitor with deoxyribonucleoside-reversible cytotoxicity.

Crona M, Codó P, Jonna VR, Hofer A, Fernandes AP, Tholander F. Crona M, et al. Among authors: tholander f. Mol Oncol. 2016 Nov;10(9):1375-1386. doi: 10.1016/j.molonc.2016.07.008. Epub 2016 Jul 26. Mol Oncol. 2016. PMID: 27511871 Free PMC article.

6

Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms.

Rudberg PC, Tholander F, Thunnissen MM, Haeggström JZ. Rudberg PC, et al. Among authors: tholander f. J Biol Chem. 2002 Jan 11;277(2):1398-404. doi: 10.1074/jbc.M106577200. Epub 2001 Oct 23. J Biol Chem. 2002. PMID: 11675384 Free article.

7

Leukotriene A4 hydrolase, insights into the molecular evolution by homology modeling and mutational analysis of enzyme from Saccharomyces cerevisiae.

Tholander F, Kull F, Ohlson E, Shafqat J, Thunnissen MM, Haeggström JZ. Tholander F, et al. J Biol Chem. 2005 Sep 30;280(39):33477-86. doi: 10.1074/jbc.M506821200. Epub 2005 Jul 15. J Biol Chem. 2005. PMID: 16024909 Free article.

8

Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.

Ahmad S, Ytterberg AJ, Thulasingam M, Tholander F, Bergman T, Zubarev R, Wetterholm A, Rinaldo-Matthis A, Haeggström JZ. Ahmad S, et al. Among authors: tholander f. J Biol Chem. 2016 Aug 26;291(35):18410-8. doi: 10.1074/jbc.M116.735647. Epub 2016 Jun 30. J Biol Chem. 2016. PMID: 27365393 Free PMC article.

9

Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates.

Rudberg PC, Tholander F, Andberg M, Thunnissen MM, Haeggström JZ. Rudberg PC, et al. Among authors: tholander f. J Biol Chem. 2004 Jun 25;279(26):27376-82. doi: 10.1074/jbc.M401031200. Epub 2004 Apr 12. J Biol Chem. 2004. PMID: 15078870 Free article.

10

Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology.

Ladds MJGW, Popova G, Pastor-Fernández A, Kannan S, van Leeuwen IMM, Håkansson M, Walse B, Tholander F, Bhatia R, Verma CS, Lane DP, Laín S. Ladds MJGW, et al. Among authors: tholander f. J Biol Chem. 2020 Dec 25;295(52):17935-17949. doi: 10.1074/jbc.RA119.012056. Epub 2020 Sep 8. J Biol Chem. 2020. PMID: 32900849 Free PMC article.

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